ΓΕΩΡΓΙΟΣ ΑΡΧΟΝΤΗΣ
ΑΡΧΟΝΤΗΣ ΓΕΩΡΓΙΟΣ
ARCHONTIS GEORGIOS
...
ASSOCIATE PROFESSOR
Department of Physics
FST 02 - Faculty of Pure and Applied Sciences
University Campus
-
22892822
22892821
www.biophys.ucy.ac.cy/phdge

Προσωπικό Προφίλ

Current position: Associate Professor, Department of Physics, University of Cyprus.Personal: Born: 22 September 1965, Athens, Greece. Family status: Married, 2 children. Education Harvard University, USA. Ph.D in Theoretical Biophysics (1994). “Statistical Mechanical Studies of Proteins”; Research supervisor: Martin Karplus.University of Athens, Greece. B.S. in Physics (1987); GPA 9.41 September 1994 – September 1996: Post-doctoral researcher, Universite Louis Pasteur, Strasbourg (Research advisor: M. Karplus). Employment History 1. University of Cyprus, 2006-today. Associate Professor, Department of Physics.2. University of Cyprus, 2002-2006. Assistant Professor, Department of Physics.3. Ecole Polytechnique, Paris, France, January 2005 – November 2005. Visiting Professor (Sabbatical leave).4. University of Cyprus, 2001-2002. Lecturer, Department of Physics.5. University of Cyprus, August 1996-2001. Lecturer, Department of Natural Sciences.6. University Louis Pasteur, Strasbourg, France, June 1994 – August 1996. Post-doctoral associate.7. Harvard University, USA, August 1988 – June 1994. Research and Teaching Assistant, Committee on Higher Degrees in Biophysics. Other Affiliations 1. Graduate Program “Masters in Bioinformatics”, Department of Biology, University of Athens. In the period 2004-2006, I have been giving a series of lectures and computational exercises, based on the Molecular Dynamics program CHARMM. I have also supervised the Masters thesis of Dr. Spyrou (January 2006), in partial fulfillment of the requirements of the program.
Our research aims to understand the properties of biomolecular systems by means of theoretical concepts, (based on statistical mechanics, continuum electrostatics, classical and quantum physics) and computational methodologies (molecular dynamics simulations with atomic-detail models, implicit-solvent models, electronic structure calculations). Some of our work is conducted in collaboration with groups at the Department of Chemistry (UC), as well as international groups in the US, France and Greece.
1. B. R. Brooks, C. L. Brooks III, A. D. Mackerell Jr., L. Nilsson, R. J. Petrella, B. Roux, Y. Won, G. Archontis, C. Bartels, S. Boresch, A. Caflisch, L. Caves, Q. Cui, A. R. Dinner, M. Feig, S. Fischer, J. Gao, M. Hodoscek, W. Im, K. Kuczera, T. Lazaridis, J. Ma, V. Ovchinnikov, E. Paci, R. W. Pastor, C. B. Post, J. Z. Pu, M. Schaefer, B. Tidor, R. M. Venable, H. L. Woodcock, X. Wu, W. Yang, D. M. York, M. Karplus (2009). CHARMM. The Biomolecular Simulation Program. J. Comp. Chem. 30:1545-1614.2. Ph. Tamamis, L-A. Abramovich, M. Reiches, K. Marshall, P. Sikorski, L. Serpell, E. Gazit and G. Archontis (2009). Self-Assembly of Phenylalanine Oligopeptides: Insights from Experiments and Simulations. Biophysical Journal 96:5020-5029.3. Ph. Tamamis, S.S. Skourtis, D. Morikis, J.D. Lambris and G. Archontis (2007). Conformational analysis of Compstatin analogues with Molecular Dynamics Simulations in Explicit Water. Journal of Molecular Graphics and Modelling 26:571-580.4. S. Polydoridis, D. Leonidas, NG. Oikonomakos and G. Archontis (2007). Recognition of Ribonuclease A by 3'-5'-Pyrophosphate-linked Dinucleotide Inhibitors: a Molecular Dynamics/Continuum Electrostatics Analysis. Biophysical Journal, 92:1659-1672.5. A. Lopes, A. Alexandrov, C. Bathelt, G. Archontis and T. Simonson (2007). Computational sidechain placement and protein mutagenesis with implicit solvent models. Proteins: Structure, Function and Bioinformatics 67:853-867.6. G. Archontis and E. Leontidis (2006). Dissecting the stabilization of iodide at the air-water interface into components: A free energy analysis. Chemical Physics Letters 420:199-203. 7. G. Archontis, E. Leontidis and G. Andreou (2005). Attraction of iodide ions by the free water surface, revealed by simulations with a polarizable force field, based on Drude oscillators. Journal of Physical Chemistry B, 109:17957-17966. 8. G. Archontis and T. Simonson (2005). A residue-pairwise Generalized Born scheme, suitable for protein design simulations. Journal of Physical Chemistry B 109:22667-22673.

Profile Information

Current position: Associate Professor, Department of Physics, University of Cyprus.Personal: Born: 22 September 1965, Athens, Greece. Family status: Married, 2 children. Education Harvard University, USA. Ph.D in Theoretical Biophysics (1994). “Statistical Mechanical Studies of Proteins”; Research supervisor: Martin Karplus.University of Athens, Greece. B.S. in Physics (1987); GPA 9.41 September 1994 – September 1996: Post-doctoral researcher, Universite Louis Pasteur, Strasbourg (Research advisor: M. Karplus). Employment History 1. University of Cyprus, 2006-today. Associate Professor, Department of Physics.2. University of Cyprus, 2002-2006. Assistant Professor, Department of Physics.3. Ecole Polytechnique, Paris, France, January 2005 – November 2005. Visiting Professor (Sabbatical leave).4. University of Cyprus, 2001-2002. Lecturer, Department of Physics.5. University of Cyprus, August 1996-2001. Lecturer, Department of Natural Sciences.6. University Louis Pasteur, Strasbourg, France, June 1994 – August 1996. Post-doctoral associate.7. Harvard University, USA, August 1988 – June 1994. Research and Teaching Assistant, Committee on Higher Degrees in Biophysics. Other Affiliations 1. Graduate Program “Masters in Bioinformatics”, Department of Biology, University of Athens. In the period 2004-2006, I have been giving a series of lectures and computational exercises, based on the Molecular Dynamics program CHARMM. I have also supervised the Masters thesis of Dr. Spyrou (January 2006), in partial fulfillment of the requirements of the program.
Our research aims to understand the properties of biomolecular systems by means of theoretical concepts, (based on statistical mechanics, continuum electrostatics, classical and quantum physics) and computational methodologies (molecular dynamics simulations with atomic-detail models, implicit-solvent models, electronic structure calculations). Some of our work is conducted in collaboration with groups at the Department of Chemistry (UC), as well as international groups in the US, France and Greece. Our research is currently funded by grants from the University of Cyprus, as well as the Cyprus Promotion Foundation. We are equipped with several Linux clusters and specialized biomolecular software (CHARMM, UHBD, MEAD, BOSS, Gaussian03).
1. B. R. Brooks, C. L. Brooks III, A. D. Mackerell Jr., L. Nilsson, R. J. Petrella, B. Roux, Y. Won, G. Archontis, C. Bartels, S. Boresch, A. Caflisch, L. Caves, Q. Cui, A. R. Dinner, M. Feig, S. Fischer, J. Gao, M. Hodoscek, W. Im, K. Kuczera, T. Lazaridis, J. Ma, V. Ovchinnikov, E. Paci, R. W. Pastor, C. B. Post, J. Z. Pu, M. Schaefer, B. Tidor, R. M. Venable, H. L. Woodcock, X. Wu, W. Yang, D. M. York, M. Karplus (2009). CHARMM. The Biomolecular Simulation Program. J. Comp. Chem. 30:1545-1614.2. Ph. Tamamis, L-A. Abramovich, M. Reiches, K. Marshall, P. Sikorski, L. Serpell, E. Gazit and G. Archontis (2009). Self-Assembly of Phenylalanine Oligopeptides: Insights from Experiments and Simulations. Biophysical Journal 96:5020 - 5029.3. Ph. Tamamis, S.S. Skourtis, D. Morikis, J.D. Lambris and G. Archontis (2007). Conformational analysis of Compstatin analogues with Molecular Dynamics Simulations in Explicit Water. Journal of Molecular Graphics and Modelling 26:571-580.4. S. Polydoridis, D. Leonidas, NG. Oikonomakos and G. Archontis (2007). Recognition of Ribonuclease A by 3'-5'-Pyrophosphate-linked Dinucleotide Inhibitors: a Molecular Dynamics/Continuum Electrostatics Analysis. Biophysical Journal, 92:1659-1672.5. A. Lopes, A. Alexandrov, C. Bathelt, G. Archontis and T. Simonson (2007). Computational sidechain placement and protein mutagenesis with implicit solvent models. Proteins: Structure, Function and Bioinformatics 67:853-867.6. G. Archontis and E. Leontidis (2006). Dissecting the stabilization of iodide at the air-water interface into components: A free energy analysis. Chemical Physics Letters 420:199-203. 7. G. Archontis, E. Leontidis and G. Andreou (2005). Attraction of iodide ions by the free water surface, revealed by simulations with a polarizable force field, based on Drude oscillators. Journal of Physical Chemistry B, 109:17957-17966. 8. G. Archontis and T. Simonson (2005). A residue-pairwise Generalized Born scheme, suitable for protein design simulations. Journal of Physical Chemistry B 109:22667-22673.