ANTONIS KIRMIZIS
Koufaris, C. & Kirmizis, A. N-Terminal Acetyltransferases Are Cancer-Essential Genes Prevalently Upregulated in Tumours. Cancers (Basel) 12(9):2631 (2020).
Demetriadou, C. et al. Histone N-alpha terminal modifications: genome regulation at the tip of the tail. Epigenetics & Chromatin, 13(1):29 (2020).
Bheda, P. et al. Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory. Molecular Cell, 78(5):915-925.e7 (2020).
Demetriadou, C. et al. NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression. Cell Death Disease, 10(3):236 (2019).
Molina-Serrano, D., Kyriakou, D., Kirmizis, A. Histone modifications as an intersection between diet and longevity. Frontiers in Genetics, 10:192 (2019).
Demetriadou, C & Kirmizis, A. Histone Acetyltransferases in Cancer: Guardians or Hazards? Critical Reviews in Oncogenesis 22:195-218 (2017).
Molina-Serrano, D & Kirmizis, A. Calorie restriction breaks an epigenetic barrier to longevity. Cell Cycle 20:1-2 (2017).
Molina-Serrano, D. et al. Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity. EMBO Rep 17(12):1829-1843 (2016).
Kyriakou, D. et al. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. BMC Biology 14(1):106 (2016).
Pavlou, D. & Kirmizis, A. Depletion of Naa40 induces p53-independent apoptosis in colorectal cancer cells via the mitochondrial pathway. Apoptosis 21:298-311 (2016).
Schiza, V. et al. N-alpha-terminal acetylation of histone H4 regulates arginine methylation and ribosomal DNA silencing. PLoS Genetics 9(9):e1003805 (2013).
Molina-Serrano, D. et al.Cross-talk among epigenetic modifications: lessons from histone arginine methylation. Biochem Soc Trans 41(3):751-759 (2013).
Kirmizis, A. et al. Distinct transcriptional outputs associated with mono- and dimethylated histone H3 arginine 2. Nature Struct Mol Biol 16, 449-451 (2009).
Kirmizis, A. et al. Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation. Nature 449, 928-32 (2007).
Kirmizis, A. et al. Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. Genes & Development 18, 1592-1605 (2004).