The study was published in the journal Cell Communication and Signaling:
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-020-00671-1?fbclid=IwAR1mg0IOPyPIZngJMgDzm0N4qEnRZZaDcvyR4fhQTrM1in6oUhkm3Yf5z_Y#Sec33

Visit the new website of the Epigenetics and Gene regulation Laboratory at: https://www.kirmizislab.com/

Visit the brand-new website of the Molecular Biology and Biochemistry Laboratory www.mbblab.net and our accounts on Twitter (@LabSantama) and Instagram (mbblabucy)!

 Please see the Presentation announcements for the current Semester

 Link : Onedrive

The recently published work of the Ecology and Biodiversity Lab and colleagues from abroad, proposes a new index for the study of how biotic communities are shaped. Until now, research on the response of species richness to area and environmental heterogeneity had not addressed possible effects of species’ differences in ecological specialization. In this work Herein the new metric, ‘ecorichness’, is introduced, that combines species richness and the position of each species in the specialists-generalists spectrum. As a case study, a data set with terrestrial isopods from 43 Aegean islands and the habitats they exploit was used. The response of ‘ecorichness’ to area, habitat diversity and the K-parameter of the Choros model, as well as its relation to the ‘Small Island Effect’ (SIE) was evaluated. The best model describing ‘ecorichness’ response to area and habitat heterogeneity was found to be a quadratic one, with peaks located at an area similar to the SIE threshold. The response of ‘ecorichness’ to area was found to be shaped mainly by the increasing contribution of specialists in the assemblages of islands larger than the SIE threshold. Overall, ‘ecorichness’ will facilitate exploration of the role of ecological specialization in the shaping of biotic communities and is expected to become an important tool for the study of the patterns they exhibit.

Link to paper: https://onlinelibrary.wiley.com/doi/10.1111/jbi.14012

A multi-omics data analysis demonstrates that protein N-terminal acetyltransferases (NATs) are commonly misregulated in different types of cancer implicating them in carcinogenesis.
The study titled 'N-Terminal Acetyltransferases Are Cancer-Essential Genes Prevalently Upregulated in Tumours' is reported in the journal Cancers (Basel).

Link to paper : https://doi.org/10.3390/cancers12092631

Researchers in the Skourides Lab secured a grant from Cyprus Seeds to help commercialize an innovative device designed in the lab that can faithfully recapitulate the tumor microenvironment and allow drug screening for anti-metastatic agents as well as research on tumor cell invasion and metastasis.

Link to website : http://www.cyprusseeds.com/2020/10/09/cyprus-seeds-announces-the-2020-21-grantees-who-are-selected-for-the-second-funding-cycle-of-the-program/

 

The study identifies regulators of maintenance and inheritance of transcriptional memory using high-throughput genetic and single-cell approaches."

Link to paper : https://www.cell.com/molecular-cell/fulltext/S1097-2765(20)30258-6

 

 

 

 

New discovery by researchers at the University of Cyprus in collaboration with the University of Heidelberg, the University of Munich and the Cyprus Institute of Neurology and Genetics, in relation to the metabolism of cholesterol in the human cells.

Please click here for the full announcement (in Greek)

 

The Department of Biological Sciences accepts applications for Teaching Assistant positions in undergraduate courses for Fall Semester 2020/2021. The call is open to Ph.D. students only. Application dates: 06/07/2020 - 17/07/2020

Interested applicants must submit their application online through the following link: https://applications.ucy.ac.cy/recruitment

Reporting New U.S. Provisional Patent Application No. 63/035,415 - Our Ref. 33303/55652/US
Title of invention: Therapeutic nanocarrier system and methods of use
Inventors: Dr. Yiota Gregoriou, Gregoria Gregoriou, Emeritus Prof. Andreas I. Constantinou