{"id":1733,"date":"2024-12-02T08:45:38","date_gmt":"2024-12-02T06:45:38","guid":{"rendered":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/?p=1733"},"modified":"2026-04-03T11:11:51","modified_gmt":"2026-04-03T08:11:51","slug":"new-publication-hadjigeorgiou-a-g-et-al-2024-npj-biol-phys-mech","status":"publish","type":"post","link":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/new-publication-hadjigeorgiou-a-g-et-al-2024-npj-biol-phys-mech\/","title":{"rendered":"New Publication Hadjigeorgiou, A.G., et al. 2024 npj Biol. Phys. Mech."},"content":{"rendered":"<p>Solid tumors harbor a complex and dynamic microenvironment that hinders the delivery and efficacy of therapeutic interventions. In this study, we developed and utilized a hybrid, discrete-continuous mathematical model to explore the interplay between solid tumor growth, immune response, tumor-induced angiogenesis, and antiangiogenic drugs. By integrating published data with anti-angiogenic drugs, we elucidate three primary mechanisms by which anti-angiogenesis influences tumor progression and treatment outcomes: reduction in tumor growth rate by mitigating and temporally delaying angiogenesis, normalization of blood vessel structure and function, and improving immune cell extravasation and activation. <a href=\"https:\/\/doi.org\/10.1038\/s44341-024-00002-2\" target=\"_blank\" rel=\"noopener\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Solid tumors harbor a complex and dynamic microenvironment that hinders the delivery and efficacy of therapeutic interventions. In this study, we developed and utilized a hybrid,<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":398,"featured_media":1734,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[46],"tags":[],"class_list":["post-1733","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-and-events"],"modified_by":"kelvege","publishpress_future_action":{"enabled":false,"date":"2026-06-12 08:58:41","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/posts\/1733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/users\/398"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/comments?post=1733"}],"version-history":[{"count":1,"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/posts\/1733\/revisions"}],"predecessor-version":[{"id":1735,"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/posts\/1733\/revisions\/1735"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/media\/1734"}],"wp:attachment":[{"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/media?parent=1733"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/categories?post=1733"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/wp-json\/wp\/v2\/tags?post=1733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}