![]() |
ΑΠΙΔΙΑΝΑΚΗΣ ΓΙΩΡΓΟΣ | |
APIDIANAKIS YIORGOS | |
... | |
ΑΝΑΠΛΗΡΩΤΗΣ/ΡΙΑ ΚΑΘΗΓΗΤΗΣ/ΡΙΑ | |
Τμήμα Βιολογικών Επιστημών | |
ΘΕΕ 02 - Σχολή Θετικών και Εφαρμοσμένων Επιστημών | |
Πανεπιστημιούπολη | |
FST02, B160 | |
+357-22893767 | |
+357-22892881 | |
CIHS.cs.ucy.ac.cy |
Προσωπικό Προφίλ
- academic positions
2020- Associate Professor of Genetics, University of Cyprus, Cyprus
2012-19 Assistant Professor of Genetics, University of Cyprus, Cyprus
2008-12 Instructor in Medicine, Harvard Medical School, Boston, USA
2008-12 Assistant in Biology, Massachusetts General Hospital, USA
2008-12 Research Staff, Shriners Hospital for Children, Boston,USA
2002-08 Postdoctoral Fellow, Harvard Medical School, USA
- education
B.S. 1994 Biology, University of Crete, Greece
M.S. 1996 Molecular Genetics, University of Crete, Greece
Ph.D. 2001 Molecular Genetics, University of Crete, Greece
- web research profiles
| |
Our goal is to establish synergisms among gene allelles, microbes and the intestinal environment that predispose for intestinal inflammation and cancer. The work of our team aims towards a deeper understanding of critical aspects of intestinal human disease, including inflammatory bowel disease and intestinal tumor formation and metastasis. We use Drosophila and human genetics, histopathology and quantitative population genetics analysis to identify the host genes, microbes and dietary factors that mediate inflammation and predispose for cancer. We model human diseases primarily in flies, subsequently in mice and we follow up with human studies based on the high degree of conservation between Drosophila and mammalian signalling pathways controlling intestinal inflammation and cancer.
Key Funding & Licensing
Loss of cell Differentiation as the trigger for Dysplasia and Tumorigenesis in the aging Drosophila midgut
Research & Innovation Foundation (Nicosia, Cyprus)
2022/02 to 2024/01| Grant to YA
Grant number: EXCELLENCE 0421/0323
Notch signaling deregulation as a causal agent for spontaneous intestinal dysplasia during aging
Fondation Sante (Athens, Greece)
2020/03 to 2022/07 | Grant to YA
Grant number: YA-Sante3
A personalized risk assessment tool for Colorectal Cancer prevention through 3-prime mRNA sequencing of normalappearing mucosa in the Cypriot population
Research Promotion Foundation (Nicosia, Cyprus)
2019/07 to 2022/06| Grant to the Cyprus Intestinal Health Study
Grant number: EXCELLENCE 1216/0523
Biomarker assessment using Fecal, Blood and Colon Biopsy samples for Colon Cancer prevention in Cyprus
National Bioethics Committee (Nicosia, Cyprus)
2019/06 | Licenced to YA and colleagues
Protocol number: EEBK/ΕΠ/2019/23
Bacteria - mouse interactions during acute infection or colonization
Cyprus Veterinary Services (Nicosia, Cyprus)
2018/11 to 2023/10 | Licenced to YA and colleagues
Protocol number: CY/EXP/PR.L6/2018
Biomarker assessment in Fecal, Blood and Colon Biopsy samples for improved diagnosis and prognosis of Colon Cancer in the Cypriot Population
National Bioethics Committee (Nicosia, Cyprus)
2016/07 to 2019/06 | Licenced to YA and colleagues
Protocol number: EEBK/ΕΠ/2015/38
Dietary and pharmacological intervention for preventing intestinal tumorigenesis
Fondation Sante (Athens, Greece)
2017/03 to 2019/02 | Grant to YA
Grant number: YA-Sante2
Bacterial interactions that establish a low inflammatory state in the Drosophila and mouse intestine
Fondation Sante (Athens, Greece)
2013/01 to 2014/12 | Grant to YA
Grant number: YA-Sante
Identifying host and microbial factors that promote intestinal inflammation and cancer using Drosophila
European Commission (Brussels, Belgium)
2012/05 to 2016/04 | Award to YA
Award number: Marie Curie CIG# 303586
Identification of Human Intestinal Bacteria that Promote or Inhibit Inflammation
U.S. Department of Defense (DC, DC, United States)
2011/08 to 2012/07 | Award to YA
Award number: PR100240
Current Lab Members
Izel Ungor (PhD Student)
Owolabi Sokefun (PhD Student)
Constantina Neophitou (postdoctoral fellow)
Kelly Katsaounou (PhD Student)
Savvas Telonis (PhD Student)
Maria Koumouri (PhD Student)
Sergio Velarde (postdoctoral fellow)
Chariclea Paraskeva (PhD thesis)Katerina Kotronarou (MSc thesis)
Styliani Lau (BSc thesis)
Zafeiro Hadjigeorgiou (BSc thesis)
Maria Pettemeridi (BSc thesis)
Alumni
Keisi Prifti (BSc thesis, 2021)
Evangelos Grivoyiannis (MSc thesis, 2021)
Panayoitis Kouis (BSc thesis, 2021)
Maria Platani (BSc thesis, 2021)
Myrofora Panagi (PhD, 2014-2020)
Gavriela Sianiou (BSc thesis, 2018; MSc thesis, 2020)
Panagiota Gianni (BSc thesis 2018; MSc thesis, 2020)
Stavria Panagidou (PhD, 2012-2019)
Eleni Kamilari (PhD Student, 2015-2019)
Antri Demetriou (MSc thesis, 2019) Christina Michail (BSc thesis, 2016; MSc thesis 2019) Androniki Giakoumi (BSc thesis, 2019)
Olympiada Georgiou (BSc thesis, 2019)
Popi Georgiades (Postdoctoral Researcher, 2016-2018)
Theodoulakis Christofi (PhD, 2012-2018)
Amalia Evangelou (BSc thesis, 2016; MSc thesis, 2018)
Sofia Kalanidou (BSc thesis, 2016; MSc 2018)
Soteroulla Ellina (BSc thesis, 2017)
Rafaella Athanasiou (BSc thesis, 2017)
Stella Irakleus (BSc thesis, 2016)
Styliani Polydorou (BSc thesis, 2016)
Alexandros Patapiou (BSc thesis, 2015)
Maria Glykenou (BSc thesis, 2015)
Maria Michail (BSc thesis, 2015)
Kalodoti Avgousti (BSc thesis, 2014)
Stelios Theofilou (BSc thesis, 2014)
Maria Dimosthenous (BSc thesis, 2014)
Panayiota Markou (internship, 2013)
Eleni Ioannidou (BSc thesis, 2013)
Ilias Tzelepis (BSc thesis, 2013)
Stefania Kapsetaki (BSc thesis, 2013)
Current Teaching
Genetics BIO-201 (Spring semester mandatory course, 2013-present)
Quantitative Human Genetics BIO-851 (Spring semester graduate course, 2022-)
Immunology BIO-471 (Fall semester mandatory course, 2013-present)
Past Teaching
Bacterial Pathogenesis BIO-372 (full semester elective course, 2014-2017)Genes, Microbes & Intestinal Environment BIO-768 (full semester graduate course, 2018-2020) | |
|
Profile Information
- academic positions
2020- Associate Professor of Genetics, University of Cyprus, Cyprus
2012-19 Assistant Professor of Genetics, University of Cyprus, Cyprus
2008-12 Instructor in Medicine, Harvard Medical School, Boston, USA
2008-12 Assistant in Biology, Massachusetts General Hospital, USA
2008-12 Research Staff, Shriners Hospital for Children, Boston,USA
2002-08 Postdoctoral Fellow, Harvard Medical School, USA
- education
B.S. 1994 Biology, University of Crete, Greece
M.S. 1996 Molecular Genetics, University of Crete, Greece
Ph.D. 2001 Molecular Genetics, University of Crete, Greece
- web research profiles | |
Our goal is to establish synergisms among gene allelles, microbes and the intestinal environment that predispose for intestinal inflammation and cancer. The work of our team aims towards a deeper understanding of critical aspects of intestinal human disease, including inflammatory bowel disease and intestinal tumor formation and metastasis. We use Drosophila and human genetics, histopathology and quantitative population genetics analysis to identify the host genes, microbes and dietary factors that mediate inflammation and predispose for cancer. We model human diseases primarily in flies, subsequently in mice and we follow up with human studies based on the high degree of conservation between Drosophila and mammalian signalling pathways controlling intestinal inflammation and cancer. Key Funding & Licensing
Loss of cell Differentiation as the trigger for Dysplasia and Tumorigenesis in the aging Drosophila midgut
Research & Innovation Foundation (Nicosia, Cyprus)
2022/02 to 2024/01| Grant to YA
Grant number: EXCELLENCE 0421/0323
Notch signaling deregulation as a causal agent for spontaneous intestinal dysplasia during aging
Fondation Sante (Athens, Greece)
2020/03 to 2022/07 | Grant to YA
Grant number: YA-Sante3
A personalized risk assessment tool for Colorectal Cancer prevention through 3-prime mRNA sequencing of normalappearing mucosa in the Cypriot population
Research Promotion Foundation (Nicosia, Cyprus)
2019/07 to 2022/06| Grant to the Cyprus Intestinal Health Study
Grant number: EXCELLENCE 1216/0523
Biomarker assessment using Fecal, Blood and Colon Biopsy samples for Colon Cancer prevention in Cyprus
National Bioethics Committee (Nicosia, Cyprus)
2019/06 | Licenced to YA and colleagues
Protocol number: EEBK/ΕΠ/2019/23
Bacteria - mouse interactions during acute infection or colonization
Cyprus Veterinary Services (Nicosia, Cyprus)
2018/11 to 2023/10 | Licenced to YA and colleagues
Protocol number: CY/EXP/PR.L6/2018
Biomarker assessment in Fecal, Blood and Colon Biopsy samples for improved diagnosis and prognosis of Colon Cancer in the Cypriot Population
National Bioethics Committee (Nicosia, Cyprus)
2016/07 to 2019/06 | Licenced to YA and colleagues
Protocol number: EEBK/ΕΠ/2015/38
Dietary and pharmacological intervention for preventing intestinal tumorigenesis
Fondation Sante (Athens, Greece)
2017/03 to 2019/02 | Grant to YA
Grant number: YA-Sante2
Bacterial interactions that establish a low inflammatory state in the Drosophila and mouse intestine
Fondation Sante (Athens, Greece)
2013/01 to 2014/12 | Grant to YA
Grant number: YA-Sante
Identifying host and microbial factors that promote intestinal inflammation and cancer using Drosophila
European Commission (Brussels, Belgium)
2012/05 to 2016/04 | Award to YA
Award number: Marie Curie CIG# 303586
Identification of Human Intestinal Bacteria that Promote or Inhibit Inflammation
U.S. Department of Defense (DC, DC, United States)
2011/08 to 2012/07 | Award to YA
Award number: PR100240
Current Lab Members
Izel Ungor (PhD Student)
Owolabi Sokefun (PhD Student)
Constantina Neophitou (postdoctoral fellow)
Kelly Katsaounou (PhD Student)
Savvas Telonis (PhD Student)
Maria Koumouri (PhD Student)
Sergio Velarde (postdoctoral fellow)
Chariclea Paraskeva (PhD thesis)
Katerina Kotronarou (MSc thesis)
Styliani Lau (BSc thesis)
Zafeiro Hadjigeorgiou (BSc thesis)
Maria Pettemeridi (BSc thesis)
Alumni
Keisi Prifti (BSc thesis, 2021)
Evangelos Grivoyiannis (MSc thesis, 2021)
Panayoitis Kouis (BSc thesis, 2021)
Maria Platani (BSc thesis, 2021)
Myrofora Panagi (PhD, 2014-2020)
Gavriela Sianiou (BSc thesis, 2018; MSc thesis, 2020)
Panagiota Gianni (BSc thesis 2018; MSc thesis, 2020)
Stavria Panagidou (PhD, 2012-2019)
Eleni Kamilari (PhD Student, 2015-2019)
Antri Demetriou (MSc thesis, 2019) Christina Michail (BSc thesis, 2016; MSc thesis 2019) Androniki Giakoumi (BSc thesis, 2019)
Olympiada Georgiou (BSc thesis, 2019)
Popi Georgiades (Postdoctoral Researcher, 2016-2018)
Theodoulakis Christofi (PhD, 2012-2018)
Amalia Evangelou (BSc thesis, 2016; MSc thesis, 2018)
Sofia Kalanidou (BSc thesis, 2016; MSc 2018)
Soteroulla Ellina (BSc thesis, 2017)
Rafaella Athanasiou (BSc thesis, 2017)
Irene Dieronitou (BSc thesis, 2014; MSc thesis, 2016)
Stella Irakleus (BSc thesis, 2016)
Styliani Polydorou (BSc thesis, 2016)
Alexandros Patapiou (BSc thesis, 2015)
Maria Glykenou (BSc thesis, 2015)
Maria Michail (BSc thesis, 2015)
Kalodoti Avgousti (BSc thesis, 2014)
Stelios Theofilou (BSc thesis, 2014)
Maria Dimosthenous (BSc thesis, 2014)
Panayiota Markou (internship, 2013)
Eleni Ioannidou (BSc thesis, 2013)
Ilias Tzelepis (BSc thesis, 2013)
Stefania Kapsetaki (BSc thesis, 2013)
Current Teaching
Genetics BIO-201 (Spring semester mandatory course, 2013-present)
Quantitative Human Genetics BIO-851 (Spring semester graduate course, 2022-)
Immunology BIO-471 (Fall semester mandatory course, 2013-present)
Past Teaching
Bacterial Pathogenesis BIO-372 (full semester elective course, 2014-2017)
Genes, Microbes & Intestinal Environment BIO-768 (full semester graduate course, 2018-2020)
| |
|