ΠΑΡΗΣ ΣΚΟΥΡΙΔΗΣ

Εργαστήριο Μοριακής Εμβρυολογίας και Κυτταρικής Βιολογίας. Ο στόχος της ερευνητικής μας ομάδας είναι να κατανοήσουμε τους μοριακούς και κυτταρικούς μηχανισμούς οι οποίοι είναι υπεύθυνοι για την δημιουργία της τρισδιάστατης δομής των ιστών και τον σχηματισμό του σχεδίου του σώματος των σπονδυλωτών. Ταυτόχρονα το εργαστήριο μας με τις εφαρμογές νανοτεχνολογίας και συγκεκριμένα με την χρήση νανοκρυστάλλων (Quantum Dots) αναπτύσσει νέες μεθόδους απεικόνισης που επιτρέπουν τη μελέτη της μορφογένεσης στο οργανισμικό, κυτταρικό και μοριακό επίπεδο.
N Christodoulou, PA Skourides, Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development. Frontiers in Cell and Developmental Biology 10, 2496, 2023
M Chatzifrangkeskou, PA Skourides, The apical ciliary adhesion complex is established at the basal foot of motile cilia and depends on the microtubule network Scientific Reports 12 (1), 19028, 2022
Stathis Hadjidemetriou, Rania Hadjisavva, Andri Christodoulou, Ismini Papageorgiou, Ioanna Panayiotou, Paris A. Skourides, Spatiotemporal Identification of Cell Divisions Using Symmetry Properties in Time-Lapse Phase Contrast Microscopy, Symmetry 14 (9), 1802, 2022
R Hadjisavva, O Anastasiou, PS Ioannou, M Zheltkova, PA Skourides , Adherens junctions stimulate and spatially guide integrin activation and extracellular matrix deposition Cell Reports 40 (3), 111091, 2022
N Christodoulou, Paris A. Skourides, Distinct spatiotemporal contribution of morphogenetic events and mechanical tissue coupling during Xenopus neural tube closure. Development 149 (13), dev200358, 2022
Christina Demetriadou, Anastasia Raoukka, Evelina Charidemou, Constantine Mylonas, Christina Michael, Swati Parekh, Costas Koufaris, Paris A. Skourides, Panagiotis Papageorgis, Peter Tessarz, Antonis Kirmizis Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance. Oncogene 41 (4), 571-585, 2022
K Kaouri, N Christodoulou, A Chakraborty, PE Méndez, Paris A Skourides, Ricardo Ruiz-Baier A new mechanochemical model for apical constriction: Coupling calcium signalling and viscoelasticity Frontiers in Systems Biology, 38, 2022
Development of a Xenopus-based assay for high-throughput evaluation of mucociliary flow bioRxiv, 2022.07. 12.499724
Ioanna Antoniades, Maria Kyriakou, Anna Charalambous, Katerina Kalalidou, Andri Christodoulou, Maria Christoforou, Paris A Skourides. FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis, Cell Communication and Signaling 19 (1), 1-22, 2021
E Michael, S Polydorides, VJ Promponas, P Skourides, G Archontis, Recognition of LD motifs by the focal adhesion targeting domains of focal adhesion kinase and proline‐rich tyrosine kinase 2‐beta: Insights from molecular dynamics simulations. Proteins: Structure, Function, and Bioinformatics 89 (1), 29-52, 2021
O Anastasiou, R Hadjisavva, PA Skourides, Mitotic cell responses to substrate topological cues are independent of the molecular nature of adhesion Science Signaling 13 (620), 2020 Cover article
K Kaouri, PK Maini, P Skourides, N Christodoulou, SJ Chapman
Journal of Mathematical Biology 2019 pp 1–34