Staff Catalogue


Medical School
Shiakoleion Educational Health Center (SEKY), 123

Associate Professor of Epidemiology and Public Health



1998: First degree (awarded by Greek universities equivalent to a Bachelor's 5-year dental degree,

Field: Dentistry. Institution: Dental School, National and Kapodistrian University of Athens, Athens, Greece.

2002: Postgraduate degree (awarded by Greek universities equivalent to a Master's 2-year degree,

Field: Biostatistics. Institution: Medical School and Department of Mathematics, National and Kapodistrian University of Athens, Athens and Department of Mathematics, University of Ioannina, Ioannina, Greece.

2008: Doctoral degree (awarded by Greek universities equivalent to a PhD degree,

Field: Epidemiology. Institution: Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece. Supervisor: Professor Angelos Hatzakis.

Title of doctoral dissertation (translation from Greek): HIV and HBV coinfection in the Greek population.

Available at:  (in Greek) and in two full-text peer-reviewed publications (one in Clinical Infectious Diseases, which ranks within the leading, high-impact scientific journals globally in the field of infectious diseases): (with an accompanied editorial at and


Postdoctoral training

Sep 2012-Mar 2014: Fellowship, following an international competition, funded by the International AIDS Society and the United States National Institute on Drug Abuse for postdoctoral training and research (

Field: Epidemiology and Sociology (regarding HIV infection in people who inject drugs).

Title: "Developing measures to study how macro-level economic and social changes may have affected HIV risk in the population of injecting drug users in Greece". Institution: National Development and Research Institutes, New York, United States. Mentor: Prof. Samuel Friedman. Selected peer-reviewed publications:, και



Certified in Public Health-CPH (Nov 2017) and recertified thereafter every two years by the United States National Board of Public Health Examiners (NBPHE). Exams (Results: 93/100, Subjects: General Principles, Biostatistics, Epidemiology, Environmental Health Sciences, Health Policy and Management, Social and Behavioral Sciences, Cross-cutting Competencies). NBPHE number 14106:


Membership in Scientific and Professional Associations

American College of Epidemiology (United States): Member (2010 - 2017) based on criteria regarding training and professional experience in epidemiology (Distinction: MACE), Fellow (2018 - today) based on significant contribution to the profession of epidemiology (research and/or leadership roles) (Distinction: FACE) (

College on Problems of Drug Dependence (United States): Regular Member (2021 - today) based on criteria regarding research and scientific work in the field of drug dependence (

Other associations: Cyprus Epidemiology and Public Health Association (President of the Interim Board), International AIDS Society, American Public Health Association, International Society for Clinical Biostatistics.


Reseach/Professional experience

Principal investigator of the project «Estimating hepatitis C burden in EU/EEA» (funded by the European Centre for Disease Prevention and Control - ECDC)

Principal investigator of BeAT Heat - «Biometereological Aspect of Thermal environment and Health: impacts on public health and on special populations to improve the quality of life and tourism sustainability» (funded by the Research Promotion Foundation, Cyprus - Excellene Hubs).

Principal investigator of the project «Genetic polymorphisms and characteristics of social networks of people who inject drugs (PWID) in Athens» [funded by the 2018 “Asklepios” Grant program of Gilead Sciences Hellas (].

Site principal investigator in Athens, Greece and in Cyprus of «Transmission Reduction Intervention Project - TRIP» (funded by the United States National Institute on Drug Abuse, National Institutes of Health): TRIP has contributed to the development of a novel and safe approach to HIV prevention.

Co-investigator of Aristotle program, which has received an award by the European Monitoring Centre for Drugs and Drug Addiction-EMCDDA and significantly contributed to curbing an HIV outbreak among people who inject drugs in Athens, Greece.

Investigator or co-investigator in systematic reviews and meta-analyses on the epidemiology (including genetic epidemiology) of communicable and non-communicable diseases with significant public health burden.

Member of the scientific staff of the Greek Centre for Disease Control and Prevention (2003 - Aug 2016) involved in HIV surveillance and prevention, in writing national epidemiological reports in Greek and in English, participating in meetings of the European Centre for Disease Control and Prevention (ECDC) and the World Health Organization (WHO), and providing services during public health emergencies.

Publications in peer-reviewed journals (January 2024): 215.

Citations (January 2024): 7159 (Google Scholar), 4777 (Scopus).

h-index (January 2024): 44 (Google Scholar), 39 (Scopus).

HIV epidemiology and prevention

Epidemiology of viral hepatitis (hepatitis B and C)

Infectious disease epidemiology and prevention

Systematic reviews-meta-analyses, umbrella reviews, and overviews in the fields of epidemiology and public health

Methodology of meta-analysis

Network meta-analyses

Genetic epidemiology and non-communicable diseases

Environmental exposures and health

1: Lee T, Buchanan AL, Katenka NV, Forastiere L, Halloran ME, Friedman SR, Nikolopoulos G. Estimating Causal Effects of HIV Prevention Interventions with Interference in Network-based Studies among People Who Inject Drugs. Ann Appl Stat. 2023 Sep;17(3):2165-2191. doi: 10.1214/22-aoas1713. Epub 2023 Sep 7. PMID: 38250709.
2: Thomadakis C, Gountas I, Duffell E, Gountas K, Bluemel B, Seyler T, Pericoli FM, Kászoni-Rückerl I, El-Khatib Z, Busch M, Schmutterer I, Vanwolleghem T, Klamer S, Plettinckx E, Mortgat L, Van Beckhoven D, Varleva T, Kosanovic Licina ML, Nemeth Blazic T, Nonković D, Theophanous F, Nemecek V, Maly M, Christensen PB, Cowan S, Rüütel K, Brummer-Korvenkontio H, Brouard C, Steffen G, Krings A, Dudareva S, Zimmermann R, Nikolopoulou G, Molnár Z, Kozma E, Gottfredsson M, Murphy N, Kondili LA, Tosti ME, Ciccaglione AR, Suligoi B, Nikiforova R, Putnina R, Jancoriene L, Seguin-Devaux C, Melillo T, Boyd A, van der Valk M, Op de Coul E, Whittaker R, Kløvstad H, Stępień M, Rosińska M, Valente C, Marinho RT, Popovici O, Avdičová M, Kerlik J, Klavs I, Maticic M, Diaz A, Del Amo J, Lundberg Ederth J, Axelsson M, Nikolopoulos G. Prevalence of chronic HCV infection in EU/EEA countries in 2019 using multiparameter evidence synthesis. Lancet Reg Health Eur. 2023 Dec 13;36:100792. doi: 10.1016/j.lanepe.2023.100792. PMID: 38188273.
3: Philippopoulos K, Pantavou K, Cartalis C, Agathangelidis I, Mavrakou T, Polydoros A, Nikolopoulos G. A novel artificial neural network methodology to produce high-resolution bioclimatic maps using Earth Observation data: A case study for Cyprus. Sci Total Environ. 2023 Oct 1;893:164734. doi: 10.1016/j.scitotenv.2023.164734. Epub 2023 Jun 9. PMID: 37302587.
4: Lee Y, Buchanan AL, Ogburn EL, Friedman SR, Halloran ME, Katenka NV, Wu J, Nikolopoulos GK. Finding influential subjects in a network using a causal framework. Biometrics. 2023 Feb 14:10.1111/biom.13841. doi: 10.1111/biom.13841. Epub ahead of print. PMID: 36788358; PMCID: PMC10423748.
5. Nikolopoulos GK, Tsantes AG. Recent HIV Infection: Diagnosis and Public Health Implications. Diagnostics (Basel). 2022 Nov 1;12(11):2657. doi: 10.3390/diagnostics12112657. PMID: 36359500; PMCID: PMC9689622.
6. Pantavou K, Delibasis KK, Nikolopoulos GK. Machine learning and features for the prediction of thermal sensation and comfort using data from field surveys in Cyprus. Int J Biometeorol. 2022 Jul 27. doi: 10.1007/s00484-022-02333-y.
7. Quattrocchi A, Tsioutis C, Demetriou A, Kyprianou T, Athanasiadou M, Silvestros V, Mamais I, Demetriou CA, Theophanous F, Soteriou S, Gregoriadou C, Anastasiou E, Kolios P, Ηaralambous C, Gregoriou I, Kalakouta O, Nikolopoulos G. Effect of vaccination on SARS-CoV-2 reinfection risk: a case-control study in the Republic of Cyprus. Public Health. 2022 Mar;204:84-86. doi: 10.1016/j.puhe.2022.01.008.
8. Gountas I, Yiasemi I, Kyprianou E, Mina C, Georgiou C, Katsioloudes P, Kouroufexi A, Demetriou A, Xenofontos E, Nikolopoulos G. Planning the hepatitis C virus elimination in Cyprus: A modeling study. World J Gastroenterol. 2021 Aug 21;27(31):5219-5231. doi: 10.3748/wjg.v27.i31.5219.
9. Piovani D, Christodoulou MN, Hadjidemetriou A, Pantavou K, Zaza P, Bagos PG, Bonovas S, Nikolopoulos GK. Effect of early application of social distancing interventions on COVID-19 mortality over the first pandemic wave: An analysis of longitudinal data from 37 countries. J Infect. 2021 Jan;82(1):133-142. doi: 10.1016/j.jinf.2020.11.033. Epub 2020 Dec 1.
10. Giallouros G, Pantavou K, Pampaka D, Pavlitina E, Piovani D, Bonovas S, Nikolopoulos GK. Drug Injection-Related and Sexual Behavior Changes in Drug Injecting Networks after the Transmission Reduction Intervention Project (TRIP): A Social Network-Based Study in Athens, Greece. Int J Environ Res Public Health. 2021 Mar 1;18(5):2388. doi: 10.3390/ijerph18052388.
11. Quattrocchi A, Mamais I, Tsioutis C, Christaki E, Constantinou C, Koliou M, Pana ZD, Silvestros V, Theophanous F, Haralambous C, Stylianou A, Sotiriou S, Athanasiadou M, Kyprianou T, Demetriou A, Demetriou CA, Kolokotroni O, Gregoriou I, Paphitou N, Panos G, Kostrikis L, Karayiannis P, Petrikkos G, Agathangelou P, Mixides G, Siakallis G, Hadjihannas L, Palazis L, Vavlitou A, Matsentidou-Timiliotou C, Koukios D, Adamidi T, Frangopoulos F, Constantinou E, Nikolopoulos G. Extensive Testing and Public Health Interventions for the Control of COVID-19 in the Republic of Cyprus between March and May 2020. J Clin Med. 2020 Nov 8;9(11):3598. doi: 10.3390/jcm9113598.
12. Pantavou K, Yiallourou AI, Piovani D, Evripidou D, Danese  S, Peyrin-Biroulet L, Bonovas S, Nikolopoulos GK. Efficacy and safety of biologic agents and tofacitinib in moderate-to-severe ulcerative colitis: A systematic overview of meta-analyses.United European Gastroenterol J. 2019 Dec;7(10):1285-1303. doi: 10.1177/2050640619883566. Epub 2019 Oct 17.
13. Nikolopoulos GK, Yiallourou AI, Argyriou C, Bonovas S, Georgiadis GS, Lazarides MK. Short Term Success of Treatments to Salvage Thrombosed or Failing Synthetic Arteriovenous Grafts in End Stage Renal Disease: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials. Eur J Vasc Endovasc Surg. 2019 Dec;58(6):921-928. doi: 10.1016/j.ejvs.2019.06.495. Epub 2019 Nov 6.
14. Charalambous I, Ioannou G, Nikolaou S, Theologou R, Yiallourou A, Papatheodorou S, Pantavou KG, Nikolopoulos GK. State of knowledge of human papillomavirus (HPV), HPV vaccine and testing: a cross-sectional study among female university students in Cyprus. Women Health. 2019 May 6:1-17. doi: 10.1080/03630242.2019.1610825. [Epub ahead of print]
15. Piovani D, Danese S, Peyrin-Biroulet L, Nikolopoulos GK, Lytras T, Bonovas S. Environmental Risk Factors for Inflammatory Bowel Diseases: an Umbrella Review of Meta-analyses. Gastroenterology. 2019 Apr 20. pii: S0016-5085(19)36709-5. doi: 10.1053/j.gastro.2019.04.016. [Epub ahead of print]
16. Nikolopoulos GK, Chanos S, Tsioptsias E, Hodges-Mameletzis I, Paraskeva D, Dedes N. HIV incidence among men who have sex with men at a community-based facility in Greece. Cent Eur J Public Health. 2019 Mar;27(1):54-57. doi: 10.21101/cejph.a4856.
17. Christou R, Michael N, Stylianou E, Yiallourou AI, Pantavou K, Nikolopoulos GK. Data on knowledge and beliefs of students, physicians and other health professionals about ethical issues in Cyprus. Data Brief. 2019 Jan 22;22:1031-1035. doi: 10.1016/j.dib.2019.01.046. eCollection 2019 Feb.
18. Pantavou K, Psiloglou B, Lykoudis S, Mavrakis A, Nikolopoulos GK. Perceived air quality and particulate matter pollution based on field survey data during a winter period. Int J Biometeorol. 2018 Dec;62(12):2139-2150. doi: 10.1007/s00484-018-1614-3. Epub 2018 Oct 26.
19. Voskarides K, Christaki E, Nikolopoulos GK. Influenza Virus-Host Co-evolution. A Predator-Prey Relationship? Front Immunol. 2018 Sep 7;9:2017. doi: 10.3389/fimmu.2018.02017. eCollection 2018.
20. Friedman SR, Williams L, Young AM, Teubl J, Paraskevis D, Kostaki E, Latkin C, German D, Mateu-Gelabert P, Guarino H, Vasylyeva TI, Skaathun B, Schneider J, Korobchuk A, Smyrnov P, Nikolopoulos G. Network Research Experiences in New York and Eastern Europe: Lessons for the Southern US in Understanding HIV Transmission Dynamics. Curr HIV/AIDS Rep. 2018 Jun;15(3):283-292. doi: 10.1007/s11904-018-0403-2.
21. Bonovas S, Nikolopoulos GK, Lytras T, Fiorino G, Peyrin-Biroulet L, Danese S. Comparative safety of systemic and low-bioavailability steroids in inflammatory bowel disease: Systematic review and network meta-analysis. Br J Clin Pharmacol. 2018 Feb;84(2):239-251. doi: 10.1111/bcp.13456. Epub 2017 Dec 1.
22. Bonovas S, Lytras T, Nikolopoulos G, Peyrin-Biroulet L, Danese S. Systematic review with network meta-analysis: comparative assessment of tofacitinib and biological therapies for moderate-to-severe ulcerative colitis. Aliment Pharmacol Ther. 2018 Feb;47(4):454-465. doi: 10.1111/apt.14449. Epub 2017 Dec 4.
23. Pantavou K, Mavrakis A, Nikolopoulos GK. Data on multiple body parameters, microclimatic variables, and subjective assessment of thermal sensation monitored in outdoor environment. Data Brief. 2017 Apr 8;12:184-187. doi: 10.1016/j.dib.2017.03.045. eCollection 2017 Jun.
24. Nikolopoulos GK, Christaki E, Paraskevis D, Bonovas S. Pre-Exposure Prophylaxis for HIV: Evidence and Perspectives. Curr Pharm Des. 2017;23(18):2579-2591. doi: 10.2174/1381612823666170329145053.
25. Nikolopoulos GK, Pavlitina E, Muth SQ, Schneider J, Psichogiou M, Williams LD, Paraskevis D, Sypsa V, Magiorkinis G, Smyrnov P, Korobchuk A, Vasylyeva TI, Skaathun B, Malliori M, Kafetzopoulos E, Hatzakis A, Friedman SR. A network intervention that locates and intervenes with recently HIV-infected persons: The Transmission Reduction Intervention Project (TRIP). Sci Rep. 2016 Dec 5;6:38100. doi: 10.1038/srep38100.
26. Nikolopoulos GK, Katsoulidou A, Kantzanou M, Rokka C, Tsiara C, Sypsa V, Paraskevis D, Psichogiou M, Friedman S, Hatzakis A. Evaluation of the limiting antigen avidity EIA (LAg) in people who inject drugs in Greece. Epidemiol Infect. 2016 Oct 26:1-12. [Epub ahead of print] PubMed PMID: 27780490.
27. Bonovas S, Fiorino G, Allocca M, Lytras T, Nikolopoulos GK, Peyrin-Biroulet L, Danese S. Biologic Therapies and Risk of Infection and Malignancy in Patients With Inflammatory Bowel Disease: A Systematic Review and Network Meta-analysis. Clin Gastroenterol Hepatol. 2016 Oct;14(10):1385-1397.e10. doi:10.1016/j.cgh.2016.04.039. PubMed PMID: 27189910.
28. Nikolopoulos GK, Kostaki EG, Paraskevis D. Overview of HIV molecular epidemiology among people who inject drugs in Europe and Asia. Infect Genet Evol. 2016 Jun 7. pii: S1567-1348(16)30241-6. doi: 10.1016/j.meegid.2016.06.017. [Epub ahead of print] Review. PubMed PMID: 27287560.
29. Pantavou KG, Lykoudis SP, Nikolopoulos GK. Milder form of heat-related symptoms and thermal sensation: a study in a Mediterranean climate. Int J Biometeorol. 2016 Jun;60(6):917-29. doi: 10.1007/s00484-015-1085-8. PubMed PMID: 26506928.
30. Hatzakis A, Sypsa V, Paraskevis D, Nikolopoulos G, Tsiara C, Micha K, Panopoulos A, Malliori M, Psichogiou M, Pharris A, Wiessing L, van de Laar M, Donoghoe M, Heckathorn DD, Friedman SR, Des Jarlais DC. Design and baseline findings of a large-scale rapid response to an HIV outbreak in people who inject drugs in Athens, Greece: the ARISTOTLE programme. Addiction. 2015 Sep;110(9):1453-67. doi: 10.1111/add.12999. PubMed PMID: 26032121; PubMed Central PMCID: PMC4854521.
31. Nikolopoulos GK, Fotiou A, Kanavou E, Richardson C, Detsis M, Pharris A, Suk JE, Semenza JC, Costa-Storti C, Paraskevis D, Sypsa V, Malliori MM, Friedman SR, Hatzakis A. National income inequality and declining GDP growth rates are associated with increases in HIV diagnoses among people who inject drugs in Europe: a panel data analysis. PLoS One. 2015 Apr 15;10(4):e0122367. doi: 10.1371/journal.pone.0122367. PubMed PMID: 25875598; PubMed Central PMCID: PMC4398461.
32. Nikolopoulos GK, Bagos PG, Tsangaris I, Tsiara CG, Kopterides P, Vaiopoulos A, Kapsimali V, Bonovas S, Tsantes AE. The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: a Mendelian randomization meta-analysis. Clin Chem Lab Med. 2014 Jul;52(7):937-50. doi: 10.1515/cclm-2013-1124. PubMed PMID: 24695040.
33. Lytras T, Nikolopoulos G, Bonovas S. Statins and the risk of colorectal cancer: an updated systematic review and meta-analysis of 40 studies. World J Gastroenterol. 2014 Feb 21;20(7):1858-70. doi: 10.3748/wjg.v20.i7.1858. PubMed PMID: 24587664; PubMed Central PMCID: PMC3930985.
34. Bonovas S, Nikolopoulos G. High-burden epidemics in Greece in the era of economic crisis. Early signs of a public health tragedy. J Prev Med Hyg. 2012 Sep;53(3):169-71. PubMed PMID: 23362624.
35. Nikolopoulos GK, Masgala A, Tsiara C, Limitsiou OK, Karnaouri AC, Dimou NL, Bagos PG. Cytokine gene polymorphisms in multiple sclerosis: a meta-analysis of 45 studies including 7379 cases and 8131 controls. Eur J Neurol. 2011 Jul;18(7):944-51. doi: 10.1111/j.1468-1331.2011.03355.x. PubMed PMID: 21299734.
36. Nikolopoulos G, Bagos P, Lytras T, Bonovas S. An ecological study of the determinants of differences in 2009 pandemic influenza mortality rates between countries in Europe. PLoS One. 2011 May 11;6(5):e19432. doi: 10.1371/journal.pone.0019432. PubMed PMID: 21589928; PubMed Central PMCID: PMC3092762.
37. Bagos PG, Nikolopoulos GK. Generalized least squares for assessing trends in cumulative meta-analysis with applications in genetic epidemiology. J Clin Epidemiol. 2009 Oct;62(10):1037-44. doi: 10.1016/j.jclinepi.2008.12.008. PubMed PMID: 19345563.
38. Nikolopoulos GK, Paraskevis D, Hatzitheodorou E, Moschidis Z, Sypsa V, Zavitsanos X, Kalapothaki V, Hatzakis A. Impact of hepatitis B virus infection on the progression of AIDS and mortality in HIV-infected individuals: a cohort study and meta-analysis. Clin Infect Dis. 2009 Jun 15;48(12):1763-71. doi: 10.1086/599110. PubMed PMID: 19435436.
39. Protopsaltis I, Nikolopoulos G, Dimou E, Brestas P, Kokkoris S, Korantzopoulos P, Melidonis A. Metabolic syndrome and its components as predictors of all-cause mortality and coronary heart disease in type 2 diabetic patients. Atherosclerosis. 2007 Nov;195(1):189-94. PubMed PMID: 17064711.
40. Nikolopoulos GK, Tsantes AE, Bagos PG, Travlou A, Vaiopoulos G. Integrin, alpha 2 gene C807T polymorphism and risk of ischemic stroke: a meta-analysis. Thromb Res. 2007;119(4):501-10. PubMed PMID: 16820192.