Staff Catalogue

PANAYIOTIS KOUTENTIS

PK
22892783
...
PROFESSOR
Department of Chemistry
FST 02 - Faculty of Pure and Applied Sciences,
University Campus

Employment

2015-present: Professor in Organic Chemistry. University of Cyprus, Nicosia. Scientific editor for ARKIVOC (active), Advances in Heterocyclic Chemistry (active), Molecules (2015-2022), Sci and Molbank (2018-2022).

2009-2015: Associate Professor in Organic Chemistry. University of Cyprus, Nicosia. Scientific editor and national representative for Arkivoc. 

2004-2009: Assistant Professor in Organic Chemistry. University of Cyprus, Nicosia.

1999-2004: Lecturer in Organic Chemistry. University of Cyprus, Nicosia.

1999: Postdoctoral Scholar. Haddon Research Group, University of Kentucky, Lexington, USA: Preparation of stable phenalenyl neutral radicals. Advisor: Professor Robert C. Haddon.

1997-1998: Postdoctoral Fellow. Exotic Materials Institute, University of California, Los Angeles (UCLA), USA: Preparation of zwitterionic tetraazapentacenes. Advisor: Professor Fred Wudl.

1997: Research Assistant. University of Bristol, United Kingdom: Preparation of conformationaly controlled polymers. Advisor: Professor Roger W. Alder.

Education

1997: PhD, Organic Chemistry, Imperial College of Science, Technology and Medicine, London. Thesis title: “The Chemistry of Thiadiazines and Dithiazoles” Advisor: Prof. Charles W. Rees.

1992: BSc (Hons) First Class, Chemistry, Imperial College of Science, Technology and Medicine, London, 1992.

  

Four areas of interest are currently under investigation:
 
  1. The synthesis and reactivity of novel and unusual S,N-heterocyclic compounds
  2. The design and synthesis of organic magnets based on radical and diradical polyazaheterocyclic systems
  3. The design and synthesis of novel conjugated and non conjugated polymers, oligomers and small molecules
  4. The design and synthesis of biologically active heteroarenes.

PATENTS

  • “Verwendung benzotriazinyl-haltiger Polymere als Ladungsspeicher” B. Häupler, U.S. Schubert, A. Wild, P.A. Koutentis and G. Zissimou, DE 102017005924 A1 (12.2018).

CHAPTERS / BOOKS (12 published chapters)

  • “1,2,5-Thiadiazoles and Related Compounds”, P.A. Koutentis, Science of Synthesis, Volume 13, Product Class 11, Editors R.C. Storr, T.L. Gilchrist, p 297-348, 2003. [INVITED AUTHOR]
  • “1,2,5-Thiadiazoles” P.A. Koutentis, Comprehensive Heterocyclic Chemistry III, Volume 5, Chapter 5.09, Volume Editor V.V. Zhdankin, p 515-565, 2008. [INVITED AUTHOR]
  • “1,3,4-Thiadiazoles” P.A. Koutentis and C.P. Constantinides, Comprehensive Heterocyclic Chemistry III, Volume 5, Chapter 5.10, Volume Editor V.V. Zhdankin, p 566-605, 2008. [INVITED AUTHOR]
  • “Thiazoles”, P.A. Koutentis and H.A. Ioannidou, Science of Synthesis Knowledge Updates 2010/1, Volume 11, Product Class 17, Editor E. Schaumann, p 267-391, 2010. [INVITED AUTHOR]
  • “Overview of Polymer and Copolymer Materials for Organic Photovoltaics” S.P. Economopoulos, G. Itskos, P.A. Koutentis and S.A. Choulis, in Organic Photovoltaics: Materials, Device Physics, and Manufacturing Technologies, Second Edition, Wiley-VCH Verlag GmbH & Co. KGaA. Edited by C. Brabec, U. Scherf, and V. Dyakonov, Chapter 1, p 3-26, 2014.
  • “Stable N- and N/S-Rich Heterocyclic Radicals: Synthesis and Applications” C.P. Constantinides and P.A. Koutentis, in Advances in Heterocyclic Chemistry: Heterocyclic Chemistry in the 21st Century: A Tribute to Alan Katritzky, Elsevier, Edited by E.F.V. Scriven and C.A. Ramsden, Volume 119, Chapter 7, p 173-207, 2016. [INVITED AUTHOR]
  • “The chemistry of non-S-oxidised 4H-1,2,6-thiadiazines” A.S. Kalogirou and P.A. Koutentis, in Targets in Heterocyclic Systems - Chemistry and Properties, Italian Chemical Society, Edited by O.A. Attanasi, P. Merino and D. Spinelli, Volume 22, Chapter 5, p 82-118, 2018. [INVITED AUTHOR]
  • “Metal-Catalyzed Direct Arylation of 1,2-Azoles” M. Koyioni and P.A. Koutentis, in Advances in Heterocyclic Chemistry, Elsevier, Edited by E.F.V. Scriven and C.A. Ramsden, Volume 129, Chapter 2, p 89-154, 2019.
  • “Bicyclic 5-6 Systems: Six and Seven Heteroatoms” M. Koyioni and P.A. Koutentis, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2020 https://doi.org/10.1016/B978-0-12-409547-2.14815-2 [INVITED AUTHOR]
  • “Bicyclic 5-6 Systems: Six and Seven Heteroatoms” M. Koyioni and P.A. Koutentis, Comprehensive Heterocyclic Chemistry IV, Volume 10, Chapter 10.14, Volume Editor F. Aldabbagh, p 586-605, 2022. [INVITED AUTHOR]
  • “Direct C-H (Het)arylation of 1,2-Heteroazoles, Heterodiazoles and Triazoles” M. Koyioni and P.A. Koutentis, Handbook of CH-Functionalization; Editor-in-Chief Dr. Debabrata Maiti, Wiley-VCH: Weinheim, CHF-0219: 2022. https://doi.org/10.1002/9783527834242.chf0219 [INVITED AUTHOR]
  • “Synthesis of linear azapentacenes” G.A. Zissimou and P.A. Koutentis, Progress in Heterocyclic Chemistry, Volume 34, Chapter 2, Volume Editors G.W. Gribble and J.A. Joule, p 35-56, 2023. https://doi.org/10.1016/B978-0-443-18939-5.00003-2

PUBLICATION LIST (181 accepted papers)

  • “Investigation of the Solvent-Dependent Photoluminescence Lineshapes in 2,2'-Bithienyl-Substituted 4H-1,2,6-Thiadiazin-4-one” S. Kasiouli, E. Theodorou, C. Kyriakou, F. Paquin, H.A. Ioannidou, P.A. Koutentis and S.C. Hayes, 2012, PENDING RESUBMISSION.
  • “1,2,4-Benzotriazinyl radical-based pole-less all-organic battery” Häupler, G.A. Zissimou, R. Burges, C. Friebe, D. Schmidt, A. Wild, P.A. Koutentis, U.S. Schubert, 2016, PENDING RESUBMISSION.
  • “Mechanistic Origins of Methyl-Driven Overhauser DNP” F.A. Perras, Y. Matsuki, S.A. Southern, T. Dubroca, D.F. Flesariu, J.V. Tol, C.P. Constantinides and P.A. Koutentis, J. Chem. Phys., 2023, ACCEPTED.
  • “The Effect of High Pressure on Polymorphs of a Derivative of Blatter’s Radical: Identification of the Structural Signatures of Subtle Phase Transitions” E.T. Broadhurst, C.J.G. Wilson, G.A. Zissimou, M.A.P. Gómez, D.L.M. Vasconcelos, C.P. Constantinides, P.A. Koutentis, A.P. Ayala and S. Parsons, Cryst. Growth Des., 2023, 23, 1915-1924. [INVITED PAPER]
  • “Deciphering the ground state of a C3-Symmetrical Blatter-type triradical by CW and pulse EPR spectroscopy” A.K. Boudalis, C.P. Constantinides, N. Chrysochos, R. Carmieli, G. Leitus, A. Kourtellaris, D.B. Lawson and P.A. Koutentis, J. Magn. Reson., 2023, 349, 107406 (article no.) 9 pages.
  • “Synthesis of 3-Bromo-4-phenylisothiazole-5-carboxylic Acid and 3-Bromoisothiazole-5-carboxylic Acid” A.S. Kalogirou and P.A. Koutentis, Molbank, 2023, 2023, M1557 (article no.) 5 pages.
  • “3-Methyl 3-Bromo-5-carbamoylisothiazole-4-carboxylate” A.S. Kalogirou and P.A. Koutentis, Molbank, 2023, 2023, M1560 (article no.) 3 pages.
  • “3-Chloro-4-(p-tolyl)isothiazole-5-carbonitrile” A.S. Kalogirou and P.A. Koutentis, Molbank, 2023, 2023, M1553 (article no.) 4 pages.
  • “Oxidations of 4H-1,2,6-thiadiazines” A.S. Kalogirou, A. Kourtellaris, P.A. Koutentis, ChemistrySelect, 2022, 7, e202204204 (article no.) 8 pages.
  • “3-(1,3-Benzothiazol-2-ylsulfanyl)-1,2,6-thiadiazinones: surrogates for 3-halo-1,2,6-thiadiazinones” A.S. Kalogirou and P.A. Koutentis, Chem. Heterocycl. Compd. (N. Y., NY, U. S.), 2022, 58, 518-523. [INVITED PAPER]
  • “6,10-Dichloro-1-oxa-4,8-dithia-7,9-diazaspiro[4.5]deca-6,9-diene” A.S. Kalogirou and P.A. Koutentis, Molbank, 2022, 2022, M1377 (article no.) 4 pages.
  • “Synthesis and evaluation of 1,2,3-dithiazole inhibitors of the nucleocapsid protein of feline immunodeficiency virus (FIV) as a model for HIV infection” T. Laitinen, T. Meili, M. Koyioni, P.A. Koutentis, A. Poso, R. Hofmann-Lehmann, C.R.M. Asquith, Bioorg. Med. Chem., 2022, 68, 116834 (article no.) 10 pages.
  • “Methyl-Driven Overhauser Dynamic Nuclear Polarization” F.A. Perras, D.F. Flesariu, S.A. Southern, C. Nicolaides, J. David Bazak, N.M. Washton, T. Trypiniotis, C.P. Constantinides, P.A. Koutentis, J. Phys. Chem. Lett. 2022, 13, 4000-4006.
  • “A First Order Phase Transition in Blatter's Radical at High Pressure” E.T. Broadhurst, C.J.G. Wilson, G.A. Zissimou, F. Nudelman, C.P. Constantinides, P.A. Koutentis and S. Parsons, Acta Crystallogr. Sect. B, 2022, 78, 107-116.
  • “(Z)-2-{[(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)amino](methylthio)methylene}malononitrile” A.S. Kalogirou and P.A. Koutentis, Molbank, 2022, 2022, M1354 (article no.) 4 pages.
  • “Reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with 2-(phenylsulfonyl)acetonitrile” K. Plakas, A.S. Kalogirou, A. Kourtellaris and P.A. Koutentis, Molbank, 2022, 2022, M1322 (article no.) 6 pages.
  • “Reactions of 4H-1,2,6-thiadiazine sulfides” A.S. Kalogirou, P.A. Koutentis, Molbank, 2022, 2022, M1321 (article no.) 5 pages.
  • “Synthesis and evaluation of novel 1,2,6-thiadiazinone kinase inhibitors as potent inhibitors of solid tumors” A.S. Kalogirou, M.P. East, T. Laitinen, C.D. Torrice, K.A. Maffuid, D.H Drewry, P.A. Koutentis, G.L. Johnson, D.J. Crona, C.R.M. Asquith, Molecules, 2021, 26, 5911 (article no.) 22 pages.
  • “Crystal Structure and Solid-State Packing of 4-Chloro-5H-1,2,3-dithiazol-5-one and 4-Chloro-5H-1,2,3-dithiazole-5-thione”, C.P. Constantinides, M. Koyioni, F. Bazzi, M. Manoli, D.B. Lawson, P.A. Koutentis, Molecules, 2021, 26, 5875 (article no.) 18 pages. [INVITED PAPER]
  • “8,8'-(Benzo[c][1,2,5]thiadiazole-4,7-diyl)bis(quinolin-4(1H)-one): A Twisted Photosensitizer with AIE Properties” E. Broumidis, C.M.S. Jones, M. Koyioni, A. Kourtellaris, G.O. Lloyd, J. Marques-Hueso, P.A. Koutentis, F. Vilela, RSC Adv., 2021, 11, 29102-29107.
  • “(E)-4-Oxo-3,4-dihydroquinazoline-2-carbaldehyde Oxime” A.S. Kalogirou, A. Kourtellaris, P.A. Koutentis, Molbank, 2021, 2021, M1233 (article no.) 6 pages.
  • “Design and evaluation of 1,2,3-dithiazoles and fused 1,2,4-dithiazines as anti-cancer agents” K.A. Maffuid, M. Koyioni, C.D. Torrice, P.A. Koutentis, D.J. Crona, C.R.M. Asquith, Bioorg. Med. Chem. Lett. 2021, 43, 128078 (article no.) 5 pages."Synthesis and chemistry of benzo[e][1,2,6]thiadiazino[3,4-b][1,4]diazepin-10(11H)-ones and related ring transformations" A.S. Kalogirou, A. Kourtellaris, P.A. Koutentis, J. Org. Chem., 2021, 86, 5702-5713.
  • “2-Amino-5-chloro-1H-pyrrole-3,4-dicarbonitrile”S. Kalogirou, P.A. Koutentis, Molbank, 2021, 2021, M1191 (article no.) 5 pages.
  • “4,5,6-Trichloropyrimidine-2-carboxamide”S. Kalogirou, P.A. Koutentis, Molbank, 2021, 2021, M1190 (article no.) 4 pages.
  • “Polymorphism in a π stacked Blatter radical: structures and magnetic properties of 3-(phenyl)-1-(pyrid-2-yl)-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl” P. Constantinides, D.B. Lawson, G.A. Zissimou, A.A. Berezin, A. Mailman, M. Manoli, A. Kourtellaris, G.M. Leitus, R. Clérac, H.M. Tuononen, P.A. Koutentis, CrystEngComm, 2020, 22, 5453-5463.
  • “1-(2-Methoxyphenyl)-3-(phenyl)-1,4-dihydro-1,2,4-benzotriazin-4-yl: A Tricky “Structure-to-Magnetism” Correlation Aided by DFT Calculations” Bazzi, A.J. Danke, D.B. Lawson, G.M. Leitus, P.A. Koutentis, C.P. Constantinides, CrystEngComm, 2020, 22, 4306-4316.
  • “Synthesis of (R) and (S)-3-chloro-5-(2,4-dimethylpiperazin-1-yl)-4H-1,2,6-thiadiazin-4-ones”S. Kalogirou, C.R.M. Asquith, P.A. Koutentis, Molbank, 2020, 2020, M1139 (article no.) 6 pages.
  • “Synthesis of 4,5,6-trichloropyrimidine-2-carbonitrile from 4,6-dichloro-2-(methylthio)pyrimidine” A. Kalogirou and P.A. Koutentis, ARKIVOC, 2020, vii, 27-35. [INVITED PAPER]
  • “Synthesis of (R) and (S)-3-chloro-5-(3-methylmorpholino)-4H-1,2,6-thiadiazin-4-ones”S. Kalogirou, C.R.M. Asquith, P.A. Koutentis, Molbank, 2020, 2020, M1128 (article no.) 6 pages. [INVITED PAPER]
  • “3,3',3''-(Benzene-1,3,5-triyl)tris(1-phenyl-1H-benzo[e][1,2,4]triazin-4-yl): A C3 symmetrical Blatter-type triradical” G.A. Zissimou, A.A. Berezin, M. Manoli, C. Nicolaides, T. Trypiniotis, P.A. Koutentis, Tetrahedron, 2020, 76, 131077 (article no.) 7 pages. [INVITED PAPER]
  • “Synthesis of 2-cyanoquinazolin-4(3H)-ones from 3',5'-dichloro-1H-spiro(quinazoline-2,4'-[1,2,6]thiadiazin)-4(3H)-ones” S. Kalogirou, A. Kourtellaris, P.A. Koutentis, ChemistrySelect, 2020, 5, 1884-1889.
  • “The Reaction of 6-(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)-4-methylcyclohexa-2,4-dien-1-one with Benzene-1,2-diamine: Synthesis and Chemistry of N-(2-Aminophenyl)-2-hydroxy-5-methylbenz-imidoyl Cyanide” Koyioni, P.A. Koutentis, Synlett, 2020, 31, 482-486.
  • “Synthesis of 2-cyanopyrimidines”S. Kalogirou, P.A. Koutentis, Molbank, 2019, 2019, M1086 (article no.) 8 pages.
  • “Reactions of Polychlorinated Pyrimidines with DABCO”S. Kalogirou, P.A. Koutentis, Molbank, 2019, 2019, M1084 (article no.) 5 pages.
  • “Synthesis and reactivity of 3',5'-dichloro-1H-spiro(quinazoline-2,4'-[1,2,6]thiadiazin)-4(3H)-ones” S. Kalogirou, A. Kourtellaris, P.A. Koutentis, Eur. J. Org. Chem., 2019, 2019, 5462-5474. [INVITED PAPER], HIGHLIGHTED IN SYNFACTS 2019, 15(10), 1111 (CONTRIBUTORS: V. SNIECKUS AND S. GOMES)
  • “Ferromagnetic Interactions in a 1D Heisenberg Linear Chain of 1-Phenyl-3,7-bis(trifluoromethyl)-1,4-dihydro-1,2,4-benzotriazin-4-yls”P. Constantinides, D.B. Lawson, A.A. Berezin, G.A. Zissimou, M. Manoli, G.M. Leitus, P.A. Koutentis, CrystEngComm, 2019, 21, 4599-4606.
  • “MS-275 Chemical Analogues Promote Hemoglobin Production and Erythroid Differentiation of K562 Cells” S. Voskou, M. Phylactides, A. Afantitis, G. Melagraki, A. Tsoumanis, P.A. Koutentis, T. Mitsidi, S.I. Mirallai, M. Kleanthous, Hemoglobin, 2019, 43, 116-121.
  • “Synthesis of 6,7-dihydropyrrolo[2,1-c][1,3]thiazino[3,2-a]pyrazine-4(11bH)-(thi)ones from 1,2-dithiolo-3-(thi)ones" V.A. Ogurtsov; Y.V. Karpychev; Y. Nelyubina; P.V. Primakov; P.A. Koutentis, O.A. Rakitin, J. Org. Chem., 2019, 2019, 4149-4158.
  • “5,5'-Thiobis(3-methoxy-4H-1,2,6-thiadiazin-4-one)”S. Kalogirou, P.A. Koutentis, Molbank, 2019, 2019, M1064 (article no.) 4 pages.
  • “3,5-Bis[5-(thiazol-2-yl)thien-2-yl]-4H-1,2,6-thiadiazin-4-one” A.S. Kalogirou, P.A. Koutentis, Molbank, 2019, 2019, M1045 (article no.) 5 pages.
  • “Regioselective Fluorination of 7-Oxo-1,2,4-benzotriazines Using Selectfluor” S.I. Mirallai, P.A. Koutentis, F. Aldabbagh, Molecules, 2019, 24, 282 (article no.) 10 pages.
  • “3-Chloro-5-(3-n-hexylthien-2-yl)-4H-1,2,6-thiadiazin-4-one” A.S. Kalogirou, P.A. Koutentis, Molbank, 2019, 2019, M1043 (article no.) 5 pages.
  • “Reaction of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine with benzyltriethylammonium chloride” S. Kalogirou, M. Manoli, P.A. Koutentis, Tetrahedron Lett., 2018, 59, 3589-3593.
  • “Redox Active Quinoidal 1,2,4-Benzotriazines” A. Zissimou, A. Kourtellaris, M. Manoli, P.A. Koutentis, J. Org. Chem., 2018, 83, 9391-9402. FEATURED IN ACS EDITORS’ CHOICE https://pubs.acs.org/doi/10.1021/acs.joc.8b01311
  • “Pd-catalyzed C-N Coupling of Primary (Het)arylamines with 5-Substituted 3-Chloro-4H-1,2,6-thiadiazin-4-ones” A.S. Kalogirou, P.A. Koutentis, Tetrahedron Lett., 2018, 59, 2653-2656.
  • “The Conversion of 5,5'-Bi(1,2,3-dithiazolylidenes) into Isothiazolo[5,4-d]isothiazoles” L.S. Konstantinova, I.V. Baranovsky, V.V. Strunyasheva, A.S. Kalogirou, V.V. Popov, K.A. Lyssenko, P.A. Koutentis, O.A. Rakitin, Molecules, 2018, 23, 1257 (article no.) 13 pages.
  • “1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors” C.R.M. Asquith, P.H. Godoi, R.M. Couñago, T. Laitinen, J.W. Scott, C.G. Langendorf, J.S. Oakhill, D.H Drewry, W.J. Zuercher, P.A. Koutentis, T.M. Willson, A.S. Kalogirou, Molecules, 2018, 23, 1221 (article no.) 23 pages.
  • “5,6,7,8-Tetrafluoro-1-(2-nitrophenyl)-3-phenyl-1H-benzo[e][1,3,4]oxadiazine” G.A. Zissimou, A. Kourtellaris, P.A. Koutentis, Molbank, 2018, 2018, M997 (article no.) 8 pages.
  • “Synthesis and Characterization of Isodiphenylfluorindone and Isodiphenylfluorindinone” G.A. Zissimou, A. Kourtellaris, P.A. Koutentis, Org. Chem., 2018, 83, 4754-4761.
  • “5,5'-Bis[5-(9-decyl-9H-carbazol-3-yl)thien-2-yl]-4H,4'H-[3,3'-bi(1,2,6-thiadiazine)]-4,4'-dione” A.S. Kalogirou, P.A. Koutentis Molbank, 2018, 2018, M987 (article no.) 5 pages.
  • “Anti-cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors” L.-A. J. Keane, S.I. Mirallai, M. Sweeney, M.P. Carty, G.A. Zissimou, A.A. Berezin, P.A. Koutentis, F. Aldabbagh Molecules, 2018, 23, 574 (article no.) 8 pages.
  • “4H-1,2,6-Thiadiazine-containing donor-acceptor conjugated polymers: synthesis, optoelectronic characterization and use in organic solar cells” C.L. Chochos,S. Kalogirou, T. Ye, E. Tatsi, A. Katsouras, G.A. Zisimou, V.G. Gregoriou, A. Avgeropoulos, P.A. Koutentis J. Mater. Chem. C, 2018, 6, 3658-3667.
  • “Oxidation of Isodiphenylfluorindine: Routes to 13-Oxoisodiphenylfluorindinium Perchlorate, and Fluorindine Cruciform Dimers” A. Zissimou, A. Kourtellaris, P.A. Koutentis Org. Lett., 2018, 20, 844-847.
  • N1-(5-Fluoro-2,4-dinitrophenyl)-N2-phenyl-4-(trifluoromethyl)benzene-1,2-diamine” G.A. Zissimou, P.A. Koutentis Molbank, 2017, 2017, M967.
  • “Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs” L. Napolitano, M. Scalise, M. Koyioni, P. Koutentis, M. Catto, I. Eberini, C. Parravicini, L. Palazzolo, L. Pisani, M. Galluccio, L. Console, A. Carotti, C. Indiveri, Pharmacol. (Amsterdam, Neth.), 2017, 143, 39-52.
  • “Emission from the stable Blatter radical” G. Karekla, P. Papagiorgis, N. Panayi, G.A. Zissimou, C.P. Constantinides, P.A. Koutentis, G. Itskos, S.C. Hayes, New J. Chem., 2017, 41, 8604-8613.
  • “Preparation of Blatter Radicals via Aza-Wittig Chemistry: The Reaction of N‑Arylimino-phosphoranes and 1-(Het)aroyl-2-aryldiazenes” A.C. Savva, G.A. Zissimou, S.I. Mirallai, A.A. Berezin, M. Demetriades, C.P. Constantinides, C. Nicolaides, T. Trypiniotis, P.A. Koutentis, Org. Chem., 2017, 82, 7564–7575.
  • “A One-pot Two-step Synthesis of 3-Deazacanthin-4-ones via Sequential Pd-catalyzed Suzuki−Miyaura and Cu-catalyzed Buchwald-Hartwig Reactions” Broumidis, P.A. Koutentis, Tetrahedron Lett., 2017, 58, 2661-2664.
  • “Two-step conversion of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine into 4,5,6-trichloropyrimidine-2-carbonitrile” S. Kalogirou, M. Manoli, P.A. Koutentis, Tetrahedron Lett., 2017, 58, 2618-2621.
  • “Synthesis of 5,5'-diarylimino quinoidal 2,2'-bithiazoles” M. Koyioni, P.A. Koutentis, Lett., 2017, 19, 174-177.
  • “4-Chloro-6-ethoxy-2-(methylthio)pyrimidine” S. Kalogirou, P.A. Koutentis, Molbank, 2017, 2017, M923.
  • “Synthesis and Photophysical Studies of a Low-Symmetry Tribenzoisothiazoloporphyrazine” D. Molina, M. El-Khouly, S. Ioannou, A.S. Kalogirou, P.A. Koutentis, Á. Sastre-Santos, J. Porphyrins Phthalocyanines, 2016, 20, 1090-1097.
  • “Evaluation of PVP/Au Nanocomposite Fibers as Heterogeneous Catalysts in Indole Synthesis” I. Savva, A.S. Kalogirou, M. Achilleos, E. Vasile, P.A. Koutentis, T. Krasia-Christoforou, Molecules, 2016, 21, 1218 (article no.) 13 pages.
  • “The acid and/or thermal mediated ring contraction of 4H-1,2,6-thiadiazines to afford 1,2,5-thiadiazoles” A. Kalogirou, A. Kourtellaris, P.A. Koutentis, Org. Lett., 2016, 18, 4056-4059.
  • “Professor Oleg Alekseevich Rakitin: A Tribute” ARKIVOC, 2017, (iii), 1-7.
  • “Structurally-Defined 3D Nanocomposite Polymer Networks: Versatile Heterogeneous Catalytic Platform in Organic Synthesis” A. Kalogirou, M. Achilleos, C. Procopiou, E. Vasile, P.A. Koutentis, T. Krasia-Christoforou, ChemistrySelects, 2016, 1, 2635–2641.
  • “Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones, very strong correlation to pleurotin and thioredoxin reductase inhibition” M. Sweeney, R. Coyle, P. Kavanagh, A. Berezin, D. Lo Re, G.A. Zissimou, P.A. Koutentis, M.P. Carty, F. Aldabbagh, Bioorg. Med. Chem., 2016, 24, 3565-3570.
  • “Substitution chemistry of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals” A. Kalogirou, P.A. Koutentis, Tetrahedron Lett., 2016, 57, 3307-3310.
  • “The suppression of columnar π-stacking in 3-adamantyl-1-phenyl-1,4-dihydrobenzo[e][1,2,4]-triazin-4-yl” P. Constantinides, A. Berezin, G.A. Zissimou, M. Manoli, G. Leitus, P.A. Koutentis, Molecules, 2016, 21, 636 (article no.) 7 pages. [INVITED PAPER]
  • “Oxidation of Tetraphenylhexaazaanthracene: Accessing a Scissor Dimer of a 16π Biscyanine” G. Zissimou, C.P. Constantinides, M. Manoli, G.K. Pieridou, S.C. Hayes, P.A. Koutentis, Org. Lett., 2016, 18, 1116-1119.
  • “The Reaction of DABCO with 4-Chloro-5H-1,2,3-dithiazoles: Synthesis and Chemistry of 4-[N-(2-Chloroethyl)piperazin-1-yl]-5H-1,2,3-dithiazoles” M. Koyioni, M. Manoli, A. Koutentis, J. Org. Chem., 2016, 81, 615-631.
  • “Regioselective geminal dichloride reactivity of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine: access to 4,4-dioxo- and dithio-ketals” A. Kalogirou, P.A. Koutentis, Tetrahedron Lett., 2016, 57, 203-205.
  • “Coordination Complexes of a Neutral 1,2,4-Benzotriazinyl Radical Ligand: Synthesis, Molecular and Electronic Structures, and Magnetic Properties” I. Morgan, A. Mansikkamäki, G.A. Zissimou, P.A. Koutentis, M. Rouzières, R. Clérac, H.M. Tuononen, Chem. Eur. J., 2015, 21, 15843-15853.
  • “The reaction of 2-amino-N'-arylbenzamidines with tetracyanoethene reinvestigated: Routes to imidazoles, quinazolines and quinolino[2',3':4,5]imidazo[1,2-c]quinazoline-8-carbonitrile” S. Mirallai, M. Manoli, P.A. Koutentis, Tetrahedron, 2015, 71, 8766-8780.
  • “The conversion of 4‑anilinoquinazoline- and 3-aryl-4-imino-3,4-dihydro-quinazoline-2-carbonitriles into benzo[4,5]imidazo[1,2-c]quinazoline-6-carbonitriles via oxidative and non-oxidative C-N couplings” S. Mirallai, P.A. Koutentis, J. Org. Chem., 2015, 80, 8329-8340.
  • “Synthesis of N-aryl-3,5-dichloro-4H-1,2,6-thiadiazin-4-imines from 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine” A. Kalogirou, M. Manoli, P.A. Koutentis, Org. Lett., 2015, 17, 4118-4121.
  • “Tetraphenylhexaazaanthracenes: 16π Weakly Antiaromatic Species with Singlet Ground States” C. Constantinides, G.A. Zissimou, A.A. Berezin, T.A. Ioannou, M. Manoli, D. Tsokkou, E. Theodorou, S.C. Hayes, P.A. Koutentis, Org. Lett., 2015, 17, 4026-4029. HIGHLIGHTED IN SYNFACTS 2015, 11(10), 1049 (CONTRIBUTORS: T. M. SWAGER AND V. SCHRÖDER)
  • “Ring transformations of 2-hydroxy-(4-chloro-5H-1,2,3-dithiazol-5-ylidineamino)arenes” A. Kalogirou, S.S. Michaelidou, M. Koyioni, P.A. Koutentis, Tetrahedron, 2015, 71, 7181-7190. [INVITED PAPER]
  • “A qualitative comparison of the reactivities of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine and 4,5-dichloro-1,2,3-dithiazolium chloride” A. Kalogirou, P.A. Koutentis, Molecules, 2015, 20, 14576-14594.
  • “1,2,3-Dithiazoles – new reversible melanin synthesis inhibitors: a chemical genomics study” Charalambous, M. Koyioni, I. Antoniades, D. Pegeioti, I. Eleftheriou, S.S. Michaelidou, S.A. Amelichev, L.S. Konstantinova, O.A. Rakitin, P.A. Koutentis, P.A. Skourides, MedChemComm, 2015, 6, 935-946. 2015 MEDCHEMCOMM HOT ARTICLE
  • “4H-1,2,6-Thiadiazin-4-one-containing small molecule donors and additive effects on their performance in solution-processed organic solar cells” F. Hermerschmidt, A. Kalogirou, J. Min, G.A. Zissimou, S.M. Tuladhar, T. Ameri, H. Faber, G. Itskos, S.A. Choulis, T.D. Anthopoulos, D.D.C. Bradley, J. Nelson, C.J. Brabec, P.A. Koutentis, J. Mater. Chem. C, 2015, 3, 2358-2365.
  • “Transformation of 2-(4-chloro-5H-1,2,3-dithiazol-5-ylideneamino)-6-ethoxy-4-phenylpyridine-3,5-dicarbonitrile into 4-aminopyrido[2,3-d]pyrimidines and 2-(pyrid-2-yl)guanidines” A. Kalogirou, S.S. Michaelidou, A.J.P. White, P.A. Koutentis, Tetrahedron, 2015, 71, 1799-1807.
  • “Spectroscopic characterization of C-4 substituted 3,5‑dichloro-4H-1,2,6-thiadiazines” E. Theodorou, H. Ioannidou, T.A. Ioannou, A.S. Kalogirou, C.P. Constantinides, M. Manoli, P.A. Koutentis, S.C. Hayes, RSC Adv., 2015, 5, 18471-18481.
  • “Synthesis of Fused 1,2,4-Dithiazines and 1,2,3,5-Trithiazepines” M. Koyioni, M. Manoli and P. Koutentis, J. Org. Chem., 2014, 79, 9717-9727.
  • “Synthesis of 2-(4H-1,2,6-thiadiazin-4-ylidene)malononitriles” A. Kalogirou and P.A. Koutentis, Tetrahedron, 2014, 70, 8334-8342.
  • “PVP-crosslinked electrospun membranes with embedded Pd and Cu2O nanoparticles as effective heterogeneous catalytic supports” I. Savva, A. Kalogirou, A. Chatzinicolaou, P. Papaphilippou, A. Pantelidou, E. Vasile, P.A. Koutentis and T. Krasia-Christoforou, RSC Adv., 2014, 4, 44911-44921.
  • “Reactions of selected 3-bromoisothiazole-5-carbonitriles with the secondary dialkylamines pyrrolidine and morpholine” A. Kalogirou and P.A. Koutentis, Tetrahedron, 2014, 70, 7092-7099. [INVITED PAPER]
  • “A Magnetostructural Investigation of an Abrupt Spin-Transition for 1-Phenyl-3-trifluoromethyl-1,4-dihydro-benzo[e][1,2,4]triazin-4-yl” C. Constantinides, A.A. Berezin, G.A. Zissimou, M. Manoli, G.M. Leitus, M. Bendikov, M.R. Probert, J.M. Rawson and P.A. Koutentis, J. Am. Chem. Soc., 2014, 136, 11906-11909. FEATURED IN JACS SPOTLIGHTS http://pubs.acs.org/doi/pdf/10.1021/ja5084738
  • “Silver Mediated Direct C-H Arylation of 3-Bromoisothiazole-5-carbonitrile” A. Kalogirou and P.A. Koutentis, Tetrahedron, 2014, 70, 6796-6802.
  • “Reinvestigating the reaction of 1H-pyrazol-5-amines with 4,5-dichloro-1,2,3-dithiazolium chloride: A route to pyrazolo[3,4-c]isothiazoles and pyrazolo[3,4-d]thiazoles” M. Koyioni, M. Manoli, M.J. Manolis and P. Koutentis, J. Org. Chem., 2014, 79, 4025-4037.
  • “Structural, Magnetic and Computational Correlations of Some Imidazolo-fused 1,2,4‑Benzotriazinyl Radicals” C.P. Constantinides, A.A. Berezin, M. Manoli, G.M. Leitus, G. Zissimou, M. Bendikov, J.M. Rawson and P.A. Koutentis, Chem. Eur. J., 2014, 20, 5388-5396. ARTICLE SELECTED FOR THE WILEY-VCH HOT TOPIC ON MAGNETIC MATERIALS http://www.wiley-vch.de/util/hottopics/magnetic/
  • “Benzotriazinyl-Mediated Controlled Radical Polymerisation of Styrene” Demetriou, A.A. Berezin, P.A. Koutentis and T. Krasia-Christoforou, Polym. Int., 2014, 63, 674-679.
  • “Effective Exchange Coupling in Alternating-Chains of a π-Extended 1,2,4-Benzotriazin-4-yl” C.P. Constantinides, A.A. Berezin, M. Manoli, G.M. Leitus, M. Bendikov, J.M. Rawson and P.A. Koutentis, New J. Chem., 2014, 38, 949-954. HIGHLIGHTED IN MEET OUR AUTHORS 03/2014 http://blogs.rsc.org/nj/2014/03/20/meet-our-authors-february-march-2014/
  • “Ring contraction of 1,3-diphenylbenzo[1,2,4]triazinyl radicals to 1,2‑diphenylbenzimidazoles” A. Berezin and P.A. Koutentis, Org. Biomol. Chem., 2014, 12, 1641-1648.
  • “Ring Transformation of (4-Chloro-5H-1,2,3-dithiazol-5-ylidene)acetonitriles to 3-Haloisothiazole-5-carbonitriles” A.S. Kalogirou, I.C. Christoforou, A. Ioannidou, M.J. Manos and P.A. Koutentis, RSC Adv., 2014, 4, 7735-7748.
  • “Route to benzo- and pyrido-fused 1,2,4-triazinyl radicals via N'-(het)aryl-N'-[2-nitro(het)aryl]-hydrazides” A.A. Berezin, Zissimou, C.P. Constantinides, Y. Beldjoudi, J.M. Rawson and P.A. Koutentis, J. Org. Chem., 2014, 79, 314-327.
  • “One-step conversion of 2-amino-N'-arylbenzamidines into 3-aryl-4-imino-3,4-dihydroquinazoline-2-carbonitriles using 4,5-dichloro-1,2,3-dithiazolium chloride” S. Mirallai, M.J. Manos and P.A. Koutentis, J. Org. Chem., 2013, 78, 9906-9913.
  • “Manipulating the singlet-triplet energy gaps of arene-fused bis(1,2,3-dithiazoles): a computational study” C. Constantinides, T.A. Ioannou, P.A. Koutentis, Polyhedron, 2013, 64, 172-180.
  • “Synthesis and properties of imidazolo-fused benzotriazinyl radicals” A. Berezin, C.P. Constantinides, S.I. Mirallai, M. Manoli, L.L. Cao, J.M. Rawson, P.A. Koutentis, Org. Biomol. Chem., 2013, 11, 6780-6795.
  • “Reactions of tetracyanoethylene with N'-arylbenzamidines: A route to 2‑phenyl-3H-imidazo[4,5-b]quinoline-9-carbonitriles” S. Mirallai, M. Manoli and P.A. Koutentis, J. Org. Chem., 2013, 78, 8655-8668. HIGHLIGHTED IN SYNFACTS 2013, 9(12), 1270 (CONTRIBUTORS: V. SNIECKUS AND T. RANTANEN)
  • “Spin-triplet excitons in 1,3-diphenyl-7-(fur-2-yl)-1,4-dihydro-1,2,4-benzotriazin-4-yl” C. Constantinides, E. Carter, D.M. Murphy, M. Manoli, G.M. Leitus, M. Bendikov, J.M. Rawson and P.A. Koutentis, Chem. Commun., 2013, 49, 8662-8664.
  • “Identifying Potential Candidates for Donor-Acceptor Copolymers on a Series of 4H-1,2,6-Thiadiazines: An Electrochemical Approach” P. Economopoulos, P.A. Koutentis, H.A. Ioannidou, S.A. Choulis, Electrochimica Acta, 2013, 107, 448-453.
  • “Novel BODIPY-based conjugated polymers donors for organic photovoltaic applications” S.P. Economopoulos, C.L. Chochos, H.A. Ioannidou, M. Neophytou, C. Charilaou, G.A. Zissimou, J.M. Frost, T. Sachetan, M. Shahid, J. Nelson, M. Heeney, D.D.C. Bradley, G. Itskos, P.A. Koutentis, S.A. Choulis, RSC Adv., 2013, 3, 10221-10229.
  • “The conversion of [(4-chloro-5H-1,2,3-dithiazol-5-ylidene)amino]azines into azine fused thiazole-2-carbonitriles” P.A. Koutentis, M. Koyioni, S.S. Michaelidou, Biomol. Chem., 2013, 11, 621-629.
  • “Antiferromagnetic Interactions in 1D Heisenberg Linear Chains of 7-(4-Fluorophenyl) and 7-Phenyl Substituted 1,3-Diphenyl-1,4-dihydro-1,2,4-benzotriazin-4-yl radicals” C.P. Constantinides, P.A. Koutentis andM. Rawson, Chem. Eur. J., 2012, 18, 15433-15438.
  • “3,5-Bis(4-dodecylthiophen-2-yl)-4H-1,2,6-thiadiazin-4-one” H.A. Ioannidou and P.A. Koutentis, Molbank, 2012, 2012, M784.
  • “From Blatter Radical to 7-Substituted 1,3-Diphenyl-1,4-dihydrothiazolo[5',4':4,5]benzo[1,2-e]-[1,2,4]triazin-4-yls: Toward Multifunctional Materials” A.A. Berezin, C.P. Constantinides, C. Drouza, M. Manoli, P.A. Koutentis, Lett., 2012, 14, 5586-5589.
  • “Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase” Catto, A.A. Berezin, D. Lo Re, G. Loizou, M. Demetriades, A. De Stradis, F. Campagna, P.A. Koutentis, A. Carotti, Eur. J. Med. Chem., 2012, 58, 84-97.
  • “Inactivation by 1,2,3-dithiazoles of the glutamine/amino acid transporter (ASCT2): a valuable approach to anticancer therapy” F. Oppedisano, M. Catto, P.A. Koutentis, O. Nicolotti, L. Pochini, M. Koyioni, A. Introcaso, S.S. Michaelidou, A. Carotti, C. Indiveri, Appl. Pharm., 2012, 265, 93-102.
  • “3-Chloro-5-(4-dodecylthiophen-2-yl)-4H-1,2,6-thiadiazin-4-one” H.A. Ioannidou and P.A. Koutentis, Molbank, 2012, 2012, M782.
  • “Synthesis of Asymmetric 3,5-Diaryl-4H-1,2,6-Thiadiazin-4-ones via Suzuki-Miyaura and Stille Coupling Reactions” H.A. Ioannidou and P.A. Koutentis, Tetrahedron, 2012, 68, 7380-7385.
  • 2-(2,3,4,5,6-Pentafluorophenyl)-1H-benzo[d]imidazole, a fluorine-rich building block for the preparation of conjugated polymer donors for organic solar cell applications” M. Neophytou, H.A. Ioannidou, A. Ioannou, C.L. Chochos, S.P. Economopoulos, P.A. Koutentis, G. Itskos, S.A. Choulis, Polym. Chem., 2012, 3, 2236-2243. TOP 10 MOST READ POLYMER CHEMISTRY ARTICLE IN JUNE 2012
  • “Ferromagnetic Interactions in a 1D Alternating Linear Chain of π-Stacked 1,3-Diphenyl-7-(thien-2-yl)-1,4-dihydro-1,2,4-benzotriazin-4-yl Radicals” C.P. Constantinides, P.A. Koutentis andM. Rawson, Chem. Eur. J., 2012, 18, 7109-7116.
  • “Substitution at C-4 in 3,5-Disubstituted 4H-1,2,6-Thiadiazin-4-ones” H.A. Ioannidou and P.A. Koutentis, Tetrahedron, 2012, 68, 2590-2597.
  • “Some Cyclization Reactions of 1,3-Diphenylbenzo[e][1,2,4]triazin-7(1H)-one: Preparation and Computational Analysis of Non Symmetrical Zwitterionic Biscyanines” A. Ioannou, P.A. Koutentis, H. Krassos, G. Loizou, D. Lo Re, Org. Biomol. Chem., 2012, 10, 1339-1348. OBC HOT ARTICLE
  • “Selective Stille Coupling Reactions of 3-Chloro-5-halo(pseudohalo)-4H-1,2,6-thiadiazin-4-ones”A. Ioannidou, C. Kizas, P.A. Koutentis, Org. Lett., 2011, 13, 5886-5889.
  • “Synthesis of [(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)amino]azines” P.A. Koutentis, M. Koyioni and S.S. Michaelidou, Molecules, 2011, 16, 8992-9002.
  • “Synthesis of Triazafluoranthenones via Silver (I) Mediated Non-oxidative and Oxidative Intramolecular Palladium Catalyzed Cyclizations” P.A. Koutentis, Loizou and D. Lo Re, J. Org. Chem., 2011, 76, 5793-5802.
  • “1,3-Diphenylbenzo[e][1,2,4]triazin-7(1H)-one: Selected Chemistry at the C-6, C-7 and C-8 Positions” A. Koutentis, H. Krassos and D. Lo Re, Org. Biomol. Chem., 2011, 9, 5228-5237.
  • “Palladium Catalyzed C-C Coupling Reactions of 3,5-Dichloro-4H-1,2,6-thiadiazin-4-one”A. Ioannidou, C. Kizas, P.A. Koutentis, Org. Lett., 2011, 13, 3466-3469.
  • “Synthesis of Sulfur Containing Analogues of the Soluble Guanylate Cyclase Inhibitor 8‑Bromo-4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one NS2028” A. Berezin, P.A. Koutentis and M.J. Manos, Tetrahedron, 2011, 67, 5437-5443.
  • “A Three-Step Synthesis of Ethyl Canthinone-3-carboxylates from Ethyl 4-Bromo-6-methoxy-1,5-naphthyridine-3-carboxylate via a Pd-Catalyzed Suzuki-Miyaura Coupling and a Cu-Catalyzed Amidation Reaction” A. Ioannidou, A. Martin, A. Gollner and P.A. Koutentis, J. Org. Chem., 2011, 76, 5113-5122.
  • “8-[2-Chloro-5-(trifluoromethyl)phenyl]-4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one” A. Berezin and P.A. Koutentis, Molbank, 2011, 2011, M728.
  • “Suzuki-Miyaura Reactions of the Soluble Guanylate Cyclase Inhibitor NS2028: A Non Product Specific Route to C-8 Substituted Analogues” A. Berezin and P.A. Koutentis, Tetrahedron, 2011, 67, 4069-4078.
  • “Regioselective Hydrodehalogenation of 3,5-Dihaloisothiazole-4-carbonitriles: Synthesis of 3-Halo-isothiazole-4-carbonitriles”A. Ioannidou and P.A. Koutentis, Tetrahedron, 2011, 67, 3348-3354.
  • “Synthesis of 7-aryl/heteraryl-1,3-diphenyl-1,2,4-benzotriazinyls via palladium catalyzed Stille and Suzuki-Miyaura reactions” C.P. Constantinides, P.A. Koutentis and G. Loizou, Biomol. Chem., 2011, 9, 3122-3125.
  • “Characterization and Magnetic Properties of a “Super Stable” Radical 1,3-Diphenyl-7-trifluoro-methyl-1,4-dihydro-1,2,4-benzotriazin-4-yl” C.P. Constantinides, P.A. Koutentis, H. Krassos, J.M. Rawson, A.J. Tasiopoulos, Org. Chem., 2011, 76, 2798-2806.
  • “Silver Mediated Palladium Catalyzed Direct C-H Arylation of 3-Bromoisothiazole-4-carbonitrile” H.A. Ioannidou and P.A. Koutentis, Lett., 2011, 13, 1510-1513.
  • “Ligand - based virtual screening procedure for the prediction and the identification of novel β-amyloid aggregation inhibitors using Kohonen maps and Counterpropagation Artificial Neural Networks” Afantitis, G. Melagraki, P.A. Koutentis, H. Sarimveis, G. Kollias, Eur. J. Med. Chem., 2011, 46, 497-508.
  • “In silico exploration for identifying structure – activity relationship of MEK inhibition and oral bioavailability for isothiazole derivatives” Melagraki, A. Afantitis, H. Sarimveis, O. Igglessi-Markopoulou, P.A. Koutentis, G. Kollias, Chem. Bio. Drug Design, 2010, 76, 397-406.
  • “3-Amino-6-ethoxy-4-phenyl-1H-pyrrolo[2,3-b]pyridine-2,5-dicarbonitrile” A. Koutentis and S.S. Michaelidou, Molbank, 2010, 2010, M691.
  • “(Z)-2-(4-Chloro-5H-1,2,3-dithiazol-5-ylideneamino)-6-ethoxy-4-phenylpyridine-3,5-dicarbonitrile” A. Koutentis and S.S. Michaelidou, Molbank, 2010, 2010, M690.
  • “The conversion of 2-cyano cyanothioformanilides into 3-aminoindole-2-carbonitriles using triphenylphosphine”A. Koutentis and S.S. Michaelidou, Tetrahedron, 2010, 66, 6032-6039.
  • “Reinvestigating the Synthesis of N-Arylbenzamidines from Benzonitriles and Anilines in the Presence of AlCl3” P.A. Koutentis, S.I. Mirallai, Tetrahedron, 2010, 66, 5134-5139.
  • “Catalytic Oxidation of N-Phenylamidrazones to 1,3-Diphenylbenzo[1,2,4]triazinyls: An Improved Synthesis of Blatter’s Radical” P.A. Koutentis and D. Lo Re, Synthesis, 2010, 2075-2079.
  • “A combined LS-SVM & MLR QSAR workflow for predicting the inhibition of CXCR3 receptor by quinazolinone analogs” Afantitis, G. Melagraki, H. Sarimveis, P.A. Koutentis, O. Igglessi-Markopoulou and G. Kollias, Molecular Diversity, 2010, 14, 225-235.
  • “Detosylation of 3-Amino-1-tosylindole-2-carbonitriles using DBU and Thiophenol” S. Michaelidou and P.A. Koutentis, Tetrahedron, 2010, 66, 3016-3023.
  • “Two-Step Total Syntheses of Canthin-6-one Alkaloids: New One-Pot Sequential Pd-Catalyzed Suzuki-Miyaura Coupling and Cu-Catalyzed Amidation Reaction” A. Gollner and P.A. Koutentis, Lett., 2010, 12, 1352-1355.
  • “The synthesis of pyrrolo[2,3-c][1,2,6]thiadiazine-5-carbonitriles from (4H-1,2,6-thiadiazin-4-ylidene)malononitriles”S. Kalogirou, P.A. Koutentis and M.D. Rikkou, Tetrahedron, 2010, 66, 1817-1820.
  • “Microwave assisted synthesis of 3-aminoindole-2-carbonitriles from anthranilonitriles via N-unprotected 2-(cyanomethylamino)benzonitriles” S.S. Michaelidou and P.A. Koutentis, Tetrahedron, 2010, 66, 685-688.
  • “The synthesis of 2-cyano cyanothioformanilides from 2-(4-chloro-5H-1,2,3-dithiazol-5-ylidene-amino)benzonitriles using DBU”S. Michaelidou and P.A. Koutentis, Synthesis, 2009, 4167-4174.
  • “The Preparation of Percyano-1,3,4-thiadiazole and Percyanothiazole via 1,2,3-Dithiazole Chemistry” I.C. Christoforou, A.S. Kalogirou and P.A. Koutentis, Tetrahedron, 2009, 65, 9967-9972.
  • tert-Butyl 3-(4-cyano-5-phenylisothiazol-3-yl)carbazate” A. Ioannidou and P.A. Koutentis, Molbank, 2009, 2009, M628.
  • “3,4,5,6,7,8,9-Heptachlorophenaleno[1,9-bc]pyrazole”K. Demetriadou and P.A. Koutentis, Molbank, 2009, 2009, M625.
  • “The conversion of 2-(4-chloro-5H-1,2,3-dithiazolylidenamino)benzonitriles into 3-aminoindole-2-carbonitriles using triphenylphosphine” S.S. Michaelidou and P.A. Koutentis, Tetrahedron, 2009, 65, 8428-8433.
  • “Predictive QSAR workflow for the in silico identification and screening of novel HDAC inhibitors” Melagraki, A. Afantitis, H. Sarimveis, P.A. Koutentis, G. Kollias and O. Igglessi-Markopoulou, Molecular Diversity, 2009, 13, 301-311.
  • “The conversion of isothiazoles into pyrazoles using hydrazine” H.A. Ioannidou and P.A. Koutentis, Tetrahedron, 2009, 65, 7023-7037.
  • “The degradation of 4,5-dichloro-1,2,3-dithiazolium chloride in wet solvents” A.S. Kalogirou and P.A. Koutentis, Tetrahedron, 2009, 65, 6859-6862.
  • “The reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with DMSO: an improved synthesis of 4-chloro-1,2,3-dithiazol-5H-one” A.S. Kalogirou and P.A. Koutentis, Tetrahedron, 2009, 65, 6855-6858.
  • “The reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with dimethylsulfonium dicyanomethylide: an improved synthesis of (4-chloro-1,2,3-dithiazolylidene)malononitrile” A.S. Kalogirou and P.A. Koutentis, Tetrahedron, 2009, 65, 6850-6854.
  • “The reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with sulfimides: a new synthesis of N-aryl-1,2,3-dithiazolimines” A.S. Kalogirou and P.A. Koutentis, Molecules, 2009, 14, 2356-2362. [INVITED PAPER]
  • “Development and Evaluation of a QSPR Model for the Prediction of Diamagnetic Susceptibility” Afantitis, G. Melagraki, H. Sarimveis, P.A. Koutentis, J. Markopoulos and O. Igglessi-Markopoulou, QSAR Comb. Sci., 2008, 27, 432-436.
  • “Identification of a series of novel derivatives as potent HCV inhibitors by a ligand – based virtual screening optimized procedure” Melagraki, A. Afantitis, H. Sarimveis, P.A. Koutentis, J. Markopoulos, O. Igglessi-Markopoulou, Bioorg. Med. Chem., 2007, 15, 7237-7247.
  • “3,4,5-Triarylisothiazoles via C-C Coupling Chemistry” C. Christoforou and P.A. Koutentis, Org. Biomol. Chem., 2007, 5, 1381-1390.
  • “Optimization of Biaryl Piperidine and 4-Amino-2-biarylurea MCH1 Receptor Antagonists using QSAR Modeling, Classification Techniques and Virtual Screening” Melagraki, A. Afantitis, H. Sarimveis, P.A. Koutentis, J. Markopoulos and O. Igglessi-Markopoulou, J. Comput. Aided Mol. Des., 2007, 21, 251-267.
  • “A novel QSPR model to predict Θ(lower critical solution temperature) in polymer solutions using molecular descriptors” Afantitis, G. Melagraki, H. Sarimveis, P.A. Koutentis, J. Markopoulos, O. Iglessi–Markopoulou, J. Mol. Model., 2007, 13, 55-64.
  • “A Novel Simple QSAR Model for the Prediction of anti-HIV Activity Using Multiple Linear Regression Analysis”, A. Afantitis, G. Melagraki, H. Sarimveis, O. Iglessi–Markopoulou, J. Markopoulos and P.A. Koutentis, Molecular Diversity, 2006, 10, 405-414.
  • “A Novel QSAR Model for Evaluating and Predicting the Inhibition Activity of Dipeptidyl Aspartyl Fluoromethylketones” Afantitis, G. Melagraki, H. Sarimveis, P.A. Koutentis, J. Markopoulos, O. Iglessi–Markopoulou, QSAR Comb. Sci., 2006, 25, 928-935.
  • “New Regiospecific Isothiazole C-C Coupling Chemistry” C. Christoforou and P.A. Koutentis, Org. Biomol. Chem., 2006, 4, 3681-3693.
  • “A Novel QSAR Model for Predicting Induction of Apoptosis by 4-Aryl-4H-chromenes” Afantitis, G. Melagraki, H. Sarimveis, P.A. Koutentis, J. Markopoulos, O. Iglessi–Markopoulou, Bioorg. Med. Chem., 2006, 14, 6686-6694.
  • “Investigation of substituent effect of 1-(3,3-diphenylpropyl)-piperidinyl phenylacetamides on CCR5 binding affinity using QSAR and virtual screening techniques”, A. Afantitis, G. Melagraki, H. Sarimveis, P.A. Koutentis, J. Markopoulos, O. Iglessi–Markopoulou, Comput. Aided Mol. Des., 2006, 20, 83-95.
  • “Prediction of Intrinsic Viscosity in Polymer - Solvent Combinations using a QSPR model” Afantitis, G. Melagraki, H. Sarimveis, P.A. Koutentis, J. Markopoulos, O. Iglessi–Markopoulou, Polymer, 2006, 47, 3240-3248.
  • “1,2,3-Dithiazole chemistry in heterocyclic synthesis”, I.C. Christoforou, P.A. Koutentis, S.S. Michaelidou, ARKIVOC, 2006 (VII) 207-223. [INVITED PAPER]
  • “The Preparation and Characterization of 5-Substituted-4-chloro-1,2,3-dithiazolium Salts and their Conversion into 4-Substituted-3-chloro-1,2,5-thiadiazoles”, P.A. Koutentis, Molecules, 2005, 10, 346-359. [INVITED PAPER]
  • “A DFT Study of the Ground State Multiplicities of Linear Angular Polyheteroacenes”, C.P. Constantinides, P.A. Koutentis, J. Schatz, J. Am. Chem. Soc., 2004, 126, 16232-16241.
  • “Regiospecific Suzuki coupling of 3,5-dichloroisothiazole-4-carbonitrile”, C. Christoforou, P.A. Koutentis, C.W. Rees, Org. Biomol. Chem., 2003, 1, 2900-2907.
  • “Liquid Crystalline Phase Behaviour in a Zwitterionic Tetraazapentacene”, E. Riley, G.W. Mitchell, P.A. Koutentis, M. Bendikov, P. Kaszynki, F. Wudl, S.H. Tolbert, Adv. Funct. Mater., 2003, 13, 531-540.
  • “Regiospecific synthesis of 5,7-disubstituted quinoxalino[2,3-b]phenazines”, P.A. Koutentis, ARKIVOC, 2002 (V) 175-191. [INVITED PAPER]
  • “Reactions of 1,2,3-dithiazoles with halogenated malononitriles”, C. Christoforou, P.A. Koutentis, C.W. Rees, J. Chem. Soc., Perkin Trans. 1, 2002, 1236-1241.
  • “Reaction of Herz salts with malononitrile: a general route to (6H‑benzo[1,2,3]dithiazol-6-ylidene)-malononitriles”A. Koutentis and C.W. Rees, J. Chem. Soc., Perkin Trans. 1, 2002, 315-319.
  • “Perchlorophenalenyl Radical, C13Cl9: A Modulated Structure with Nine Threefold-Symmetric Molecules in the Asymmetric Unit” P.A. Koutentis, R.C. Haddon, R.T. Oakley, A.W. Cordes and C.P. Brock, Acta Cryst. 2001, B57, 680-691.
  • “Perchlorophenalenyl Radical” A. Koutentis, Y. Chen, Y. Cao, T.P. Best, M.E. Itkis, L. Beer, R.T. Oakley, A.W. Cordes, C.P. Brock, and R.C. Haddon, J. Am. Chem. Soc., 2001, 123, 3864-3871.
  • “Cyclisation chemistry of 4H-1,2,6-thiadiazines” P.A. Koutentis and C.W. Rees, Chem. Soc., Perkin Trans. 1, 2000, 2601-2607.
  • “Chemistry of 4-dicyanomethyleno-1,2,6-thiadiazines” P.A. Koutentis and C.W. Rees, Chem. Soc., Perkin Trans. 1, 2000, 1081-1088.
  • “Reaction of tetracyanoethylene with SCl2; new molecular rearrangements” P.A. Koutentis and C.W. Rees, Chem. Soc., Perkin Trans. 1, 2000, 1089-1094.
  • “Reaction of tetracyanoethylene with SCl2; new molecular rearrangements” P.A. Koutentis, C.W. Rees, A.J.P. White and D.J. Williams, Chem. Soc., Chem. Commun., 2000, 303-304.
  • “Polyazaacenes: new tricks for old dogs” F. Wudl, P.A. Koutentis, A. Weitz, B. Ma, T. Strassner, K.N. Houk and S.I. Khan, Pure Appl. Chem., 1999, 71, 295-302.
  • “Chemistry of 4-chloro-5-cyano-1,2,3-dithiazolium chloride” P.A. Koutentis and C.W. Rees, Chem. Soc., Perkin Trans. 1, 1999, 111-117.
  • “Conversion of a 1,2,3-dithiazole into a 3H-pyrrole-3-thione and a 3H-pyrrol-3-ylidene-phosphorane” P.A. Koutentis, C.W. Rees, A.J.P. White and D.J. Williams, Chem. Soc., Perkin Trans. 1, 1998, 2765-2769.
  • “Reactions of tetracyanoethylene oxide with 1,2,3-dithiazoles” P.A. Koutentis and C.W. Rees, Chem. Soc., Perkin Trans. 1, 1998, 2505-2509.
  • “Polymers and oligomers with transverse aromatic groups and strongly constrained chain conformations” R.W. Alder, K.R. Anderson, P.A. Benjes, C.P. Butts, P.A. Koutentis and A. Guy Orpen, Chem. Soc., Chem. Commun., 1998, 309-310.
  • “New routes to benzothiazoles, isothiazoles and 1,2,3-dithiazoles” K. Emayan, R.F. English, P.A. Koutentis and C.W. Rees, Chem. Soc., Perkin Trans. 1, 1997, 3345-3349.

 PROCEEDINGS/MONOGRAPHS (NON-REFEREED)

  • “Effects of substitution on the ground-state multiplicities of zwitterionic polyazaacenes: A DFT study combined with broken symmetry approach” C.P. Constantinides and P.A. Koutentis, Proceedings of the International Conference on the Science and Technology of Synthetic Metals (ICSM 2004), University of Wollongong, 2004, ISBN 1741280613.
  • “New routes to azafluoranthenes” P.A. Koutentis, A. Gollner, D. Lo Re, G. Loizou, IV International Conference of the CBC series “Modern Aspects of Chemistry of Heterocycles” ICSPF PRESS, St Petersburg, 2010, ISBN 978-5-903078-16-5.
  • “Recent advances in 3,5-dichloro-4H-1,2,6-thiadiazin-4-one chemistry” A. Ioannidou, P.A. Koutentis, in book “Chemistry of Heterocyclic Compounds. Modern Aspects”, Moscow: ICSPF, 2014, vol. 1, p. 25-32.
  • “Synthesis of Biological Compounds Against Alzheimer’s Disease” A. Koutentis, Book of Abstracts of The Trends in Drug Research 32nd Cyprus-Noordwijkerhout-Camerino Symposium, Quintessence Enterprises Ltd, Limassol, Cyprus, 2014, p. 78-83, ISBN 978-9963-9615-3-5.