{"id":8849,"date":"2025-11-12T11:59:03","date_gmt":"2025-11-12T08:59:03","guid":{"rendered":"https:\/\/www.ucy.ac.cy\/pr\/?p=8849"},"modified":"2025-11-12T11:59:03","modified_gmt":"2025-11-12T08:59:03","slug":"chat-t","status":"publish","type":"post","link":"https:\/\/www.ucy.ac.cy\/pr\/chat-t\/","title":{"rendered":"\u039c\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03af\u03bf\u03c5 \u039a\u03cd\u03c0\u03c1\u03bf\u03c5 \u03bc\u03b5 \u03c4\u03b7\u03bd \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03a3\u03c7\u03bf\u03bb\u03ae \u03c4\u03bf\u03c5 \u03a7\u03ac\u03c1\u03b2\u03b1\u03c1\u03bd\u03c4 \u03b1\u03c0\u03bf\u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03b9 \u03bd\u03ad\u03b5\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03bc\u03b5 CAR-T \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c3\u03b5 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2, 12 \u039d\u03bf\u03b5\u03bc\u03b2\u03c1\u03af\u03bf\u03c5 2025"},"content":{"rendered":"<p><em>Andreas G. Hadjigeorgiou, Lance L. Munn, Triantafyllos Stylianopoulos, Rakesh K. Jain<\/em><strong>\u00a0<\/strong><\/p>\n<p><strong>\u0397 \u03a0\u03c1\u03cc\u03ba\u03bb\u03b7\u03c3\u03b7: \u03a0\u03ce\u03c2 \u03c4\u03b1 CAR-T \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b1\u03b3\u03b5\u03af\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2<\/strong><\/p>\n<p><a href=\"https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CAR-T-12-11-2025.pdf\">\u039c\u03b9\u03b1 \u03c0\u03c1\u03c9\u03c4\u03bf\u03c0\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03af\u03bf\u03c5 \u039a\u03cd\u03c0\u03c1\u03bf\u03c5<\/a>, \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b5\u03c1\u03b3\u03b1\u03c3\u03af\u03b1 \u03bc\u03b5 \u03c4\u03bf \u0393\u03b5\u03bd\u03b9\u03ba\u03cc \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u03c4\u03b7\u03c2 \u039c\u03b1\u03c3\u03b1\u03c7\u03bf\u03c5\u03c3\u03ad\u03c4\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03a3\u03c7\u03bf\u03bb\u03ae \u03c4\u03bf\u03c5 \u03a7\u03ac\u03c1\u03b2\u03b1\u03c1\u03bd\u03c4, \u03b4\u03b7\u03bc\u03bf\u03c3\u03b9\u03b5\u03cd\u03c4\u03b7\u03ba\u03b5 \u03c3\u03c4\u03bf \u03ad\u03b3\u03ba\u03c1\u03b9\u03c4\u03bf \u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03bf\u03bd\u03b9\u03ba\u03cc \u03c0\u03b5\u03c1\u03b9\u03bf\u03b4\u03b9\u03ba\u03cc PNAS (Proceedings of the National Academy of Sciences).<\/p>\n<p>\u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bc\u03b5 \u03c4\u03af\u03c4\u03bb\u03bf: \u00abPhysiologically-based pharmacokinetic model for CAR-T cell delivery and efficacy in solid tumors\u00bb, \u03b4\u03b9\u03b5\u03ba\u03c0\u03b5\u03c1\u03b1\u03b9\u03ce\u03b8\u03b7\u03ba\u03b5 \u03bc\u03b5 \u03b5\u03c0\u03b9\u03ba\u03b5\u03c6\u03b1\u03bb\u03ae\u03c2 \u03c4\u03bf\u03c5\u03c2 \u0394\u03c1. Rakesh K. Jain (\u0393\u03b5\u03bd\u03b9\u03ba\u03cc \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u039c\u03b1\u03c3\u03b1\u03c7\u03bf\u03c5\u03c3\u03ad\u03c4\u03b7\u03c2\/\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03a3\u03c7\u03bf\u03bb\u03ae \u03a7\u03ac\u03c1\u03b2\u03b1\u03c1\u03bd\u03c4) \u03ba\u03b1\u03b9 \u0394\u03c1. \u03a4\u03c1\u03b9\u03b1\u03bd\u03c4\u03ac\u03c6\u03c5\u03bb\u03bb\u03bf \u03a3\u03c4\u03c5\u03bb\u03b9\u03b1\u03bd\u03cc\u03c0\u03bf\u03c5\u03bb\u03bf (\u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03bf \u039a\u03cd\u03c0\u03c1\u03bf\u03c5), \u03c0\u03c1\u03ce\u03c4\u03bf \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03ad\u03b1 \u03c4\u03bf\u03bd \u0394\u03c1. \u0391\u03bd\u03b4\u03c1\u03ad\u03b1 \u03a7\u03b1\u03c4\u03b6\u03b7\u03b3\u03b5\u03c9\u03c1\u03b3\u03af\u03bf\u03c5 (\u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b9\u03bf \u039a\u03cd\u03c0\u03c1\u03bf\u03c5) \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03c4\u03bf\u03c5 \u0394\u03c1. Lance L. Munn (\u0393\u03b5\u03bd\u03b9\u03ba\u03cc \u039d\u03bf\u03c3\u03bf\u03ba\u03bf\u03bc\u03b5\u03af\u03bf \u039c\u03b1\u03c3\u03b1\u03c7\u03bf\u03c5\u03c3\u03ad\u03c4\u03b7\u03c2\/\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03a3\u03c7\u03bf\u03bb\u03ae \u03a7\u03ac\u03c1\u03b2\u03b1\u03c1\u03bd\u03c4). \u03a3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b4\u03b9\u03b5\u03c1\u03b5\u03c5\u03bd\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b7 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd CAR-T \u03c3\u03b5 \u03c3\u03c5\u03bc\u03c0\u03b1\u03b3\u03b5\u03af\u03c2 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2, \u03cc\u03c0\u03c9\u03c2 \u03c4\u03bf \u03b3\u03bb\u03bf\u03b9\u03bf\u03b2\u03bb\u03ac\u03c3\u03c4\u03c9\u03bc\u03b1, \u03ba\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03c9\u03b8\u03b5\u03af \u03bc\u03ad\u03c3\u03c9 \u03bf\u03bc\u03b1\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03b1\u03b3\u03b3\u03b5\u03af\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5.<\/p>\n<p>\u0397 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 CAR-T \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03bf\u03c2 \u03bc\u03bf\u03c1\u03c6\u03ae \u03b1\u03bd\u03bf\u03c3\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2, \u03cc\u03c0\u03bf\u03c5 \u03c4\u03b1 \u03af\u03b4\u03b9\u03b1 \u03c4\u03b1 \u03a4- \u03bb\u03b5\u03bc\u03c6\u03bf\u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03bf\u03cd\u03c2 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03ad\u03c6\u03bf\u03c5\u03bd \u03c4\u03b1 \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1. \u0397 \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 \u03b1\u03c5\u03c4\u03ae \u03ad\u03c7\u03b5\u03b9 \u03c6\u03ad\u03c1\u03b5\u03b9 \u03b5\u03c0\u03b1\u03bd\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03b1\u03b9\u03bc\u03b1\u03c4\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ce\u03bd \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03c9\u03bd, \u03c9\u03c3\u03c4\u03cc\u03c3\u03bf \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03b5 \u03c3\u03c5\u03bc\u03c0\u03b1\u03b3\u03b5\u03af\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7 \u03bb\u03cc\u03b3\u03c9 \u03b1\u03bd\u03c9\u03bc\u03b1\u03bb\u03b9\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5. \u0391\u03bd\u03c9\u03bc\u03b1\u03bb\u03af\u03b5\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b4\u03bf\u03bc\u03ae \u03c4\u03c9\u03bd \u03ba\u03b1\u03c1\u03ba\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03b1\u03b3\u03b3\u03b5\u03af\u03c9\u03bd, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5 \u03c3\u03b5 \u03ba\u03bf\u03bb\u03bb\u03b1\u03b3\u03cc\u03bd\u03bf \u03ba\u03b1\u03b9 \u03c5\u03b1\u03bb\u03bf\u03c5\u03c1\u03bf\u03bd\u03b9\u03ba\u03cc \u03bf\u03be\u03cd, \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7 \u03b4\u03b9\u03b5\u03af\u03c3\u03b4\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03cc\u03c3\u03bf \u03c4\u03c9\u03bd \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd CAR-T \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd. \u0397 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\u03c5\u03c0\u03bf\u03bb\u03bf\u03b3\u03b9\u03c3\u03c4\u03b9\u03ba\u03bf\u03cd \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf\u03c5 \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03b5\u03bd\u03c3\u03c9\u03bc\u03b1\u03c4\u03ce\u03bd\u03b5\u03b9 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ac \u03c4\u03bf\u03c5\u03c2 \u03b3\u03b9\u03b1\u03c4\u03c1\u03bf\u03cd\u03c2 \u03bd\u03b1 \u03c3\u03c7\u03b5\u03b4\u03b9\u03ac\u03b6\u03bf\u03c5\u03bd \u03c0\u03b9\u03bf \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2.<\/p>\n<p>\u0395\u03bd \u03ba\u03b1\u03c4\u03b1\u03ba\u03bb\u03b5\u03af\u03b4\u03b9, \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03b1\u03c5\u03c4\u03ae \u03b1\u03bd\u03b1\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03cd\u03bd\u03b1\u03bc\u03b7 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03bf\u03bb\u03bf\u03b3\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b1\u03b8\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bc\u03bf\u03bd\u03c4\u03b5\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u03c9\u03c2 \u03b5\u03c1\u03b3\u03b1\u03bb\u03b5\u03af\u03bf \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03bd\u03cc\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03af\u03ba\u03b5\u03c5\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03ba\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5, \u03b1\u03bd\u03bf\u03af\u03b3\u03bf\u03bd\u03c4\u03b1\u03c2 \u03bd\u03ad\u03bf\u03c5\u03c2 \u03bf\u03c1\u03af\u03b6\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c0\u03b9\u03bf \u03b1\u03c3\u03c6\u03b1\u03bb\u03b5\u03af\u03c2, \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03c3\u03b5 \u03c3\u03c5\u03bc\u03c0\u03b1\u03b3\u03b5\u03af\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2.<\/p>\n<p>\u0393\u03b9\u03b1 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af\u03c4\u03b5 \u03bd\u03b1 \u03b2\u03c1\u03b5\u03af\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b4\u03b7\u03bc\u03bf\u03c3\u03af\u03b5\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf \u0395\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03bf \u0392\u03b9\u03bf\u03c6\u03c5\u03c3\u03b9\u03ba\u03ae\u03c2 \u03c4\u03bf\u03c5 \u039a\u03b1\u03c1\u03ba\u03af\u03bd\u03bf\u03c5 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03ba\u03ac\u03c4\u03c9 \u03c3\u03c5\u03bd\u03b4\u03ad\u03c3\u03bc\u03bf\u03c5\u03c2:<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1073\/pnas.2522634122\">https:\/\/doi.org\/10.1073\/pnas.2522634122<\/a><\/p>\n<p><a href=\"https:\/\/www.ucy.ac.cy\/cancer-biophysics\/the-lab\/\">https:\/\/www.ucy.ac.cy\/cancer-biophysics\/the-lab\/<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-8850\" src=\"https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-300x225.jpg 300w, https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-1024x766.jpg 1024w, https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-768x575.jpg 768w, https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-1536x1150.jpg 1536w, https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-2048x1533.jpg 2048w, https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-100x75.jpg 100w, https:\/\/www.ucy.ac.cy\/pr\/wp-content\/uploads\/sites\/143\/2025\/11\/CART-graph-480x359.jpg 480w\" sizes=\"auto, (max-width:767px) 300px, 300px\" \/><\/p>\n<p><strong>\u03a3\u03c7\u03ae\u03bc\u03b1:<\/strong> \u0397 \u03bf\u03bc\u03b1\u03bb\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b1\u03b3\u03b3\u03b5\u03af\u03c9\u03bd (vascular normalization) \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5 \u03c3\u03c4\u03c1\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5 (stroma normalization) \u03ba\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03b1\u03c5\u03c4\u03ac \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03c4\u03c9\u03bd CAR-T \u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03ba\u03b1\u03b9 \u03c4\u03c9\u03bd \u03c5\u03c0\u03bf\u03bb\u03bf\u03af\u03c0\u03c9\u03bd \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03c5\u03c4\u03c4\u03ac\u03c1\u03c9\u03bd \u03c3\u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03c0\u03b5\u03c1\u03b9\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd \u03c4\u03bf\u03c5 \u03cc\u03b3\u03ba\u03bf\u03c5.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Andreas G. Hadjigeorgiou, Lance L. Munn, Triantafyllos Stylianopoulos, Rakesh K. Jain\u00a0 \u0397 \u03a0\u03c1\u03cc\u03ba\u03bb\u03b7\u03c3\u03b7: \u03a0\u03ce\u03c2 \u03c4\u03b1 CAR-T \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf\u03c5\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b1\u03b3\u03b5\u03af\u03c2 \u03cc\u03b3\u03ba\u03bf\u03c5\u03c2 \u039c\u03b9\u03b1 \u03c0\u03c1\u03c9\u03c4\u03bf\u03c0\u03bf\u03c1\u03b9\u03b1\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c4\u03bf\u03c5 \u03a0\u03b1\u03bd\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03af\u03bf\u03c5<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":220,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[196,211],"tags":[],"class_list":["post-8849","post","type-post","status-publish","format-standard","hentry","category-196","category-211"],"modified_by":"dionysd","publishpress_future_action":{"enabled":false,"date":"2026-06-11 15:27:02","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/posts\/8849","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/users\/220"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/comments?post=8849"}],"version-history":[{"count":1,"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/posts\/8849\/revisions"}],"predecessor-version":[{"id":8852,"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/posts\/8849\/revisions\/8852"}],"wp:attachment":[{"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/media?parent=8849"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/categories?post=8849"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ucy.ac.cy\/pr\/wp-json\/wp\/v2\/tags?post=8849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}